Background Certain symptoms associated with infertility are associated with cardiovascular
disease, including menstrual cycle irregularity, early menopause, and obesity; however, few …

Summary Background Primary Ovarian Insufficiency (POI), a public health problem, affects 1-
3.7% of women under 40 yielding infertility and a shorter lifespan. Most causes are …

Cultivating awareness for reproduction as a window to future health presents an opportunity
for early identification and modification of risk factors that can affect both individual and …

Objective To investigate the association of infertility with atherosclerotic cardiovascular
disease (ASCVD) among postmenopausal participants in the Women's Health Initiative …

Importance Fertility status is a marker for future health, and infertility has been associated
with risk for later cancer and diabetes, but associations with midlife cardiovascular health …

Purpose To evaluate the association of a history of infertility with long-term weight, body
composition, and blood pressure. Methods We studied 1581 women from the prospective …

Objective To investigate the association between infertility and the incidence of invasive
cancer. Design Prospective cohort study (1989–2015). Setting Not applicable. Patient (s) A …

STUDY QUESTION Is fecundity, measured as time to pregnancy (TTP), associated with
mortality in parents? SUMMARY ANSWER Prolonged TTP is associated with increased …

Objective The aim of the study is to examine longitudinal associations of history of infertility
with menopausal symptoms in midlife. Methods Six hundred ninety-five midlife women (≥ …

Impaired function of the hypothalamic-pituitary-gonadal (HPG) axis can lead to a vast array
of reproductive disorders some of which are inherited or acquired, but many are of unknown …