[HTML][HTML] Transient receptor potential (TRP) ion channels in orofacial pain

Y Luo, A Suttle, Q Zhang, P Wang, Y Chen - Molecular neurobiology, 2021 - Springer
Orofacial pain, including temporomandibular joint disorders pain, trigeminal neuralgia,
dental pain, and debilitating headaches, affects millions of Americans each year with …

[HTML][HTML] Sensory neuron-TRPV4 modulates temporomandibular disorder pain via CGRP in mice

A Suttle, P Wang, FC Dias, Q Zhang, Y Luo… - The journal of pain, 2023 - Elsevier
Temporomandibular disorder (TMD) pain that involves inflammation and injury in the
temporomandibular joint (TMJ) and/or masticatory muscle is the most common form of …

[HTML][HTML] A novel murine model of mania

X Li, B Chen, D Zhang, S Wang, Y Feng, X Wu… - Molecular …, 2023 - nature.com
Neuropathological mechanisms of manic syndrome or manic episodes in bipolar disorder
remain poorly characterised, as the research progress is severely limited by the paucity of …

Phosphorylation of TRPV1 S801 contributes to modality-specific hyperalgesia in mice

J Joseph, L Qu, S Wang, M Kim, D Bennett… - Journal of …, 2019 - Soc Neuroscience
Transient receptor potential vanilloid subtype 1 (TRPV1) is a nonselective cationic channel
activated by painful stimuli such as capsaicin and noxious heat, and enriched in sensory …

[HTML][HTML] Methods used and application of the mouse grimace scale in biomedical research 10 years on: a scoping review

AL Whittaker, Y Liu, TH Barker - Animals, 2021 - mdpi.com
Simple Summary The Mouse Grimace Scale (MGS) was developed as a tool for the
measurement of pain in laboratory mice. There have been a number of studies focused on …

[HTML][HTML] The neurobiology of pain and facial movements in rodents: Clinical applications and current research

A Domínguez-Oliva, D Mota-Rojas… - Frontiers in veterinary …, 2022 - frontiersin.org
One of the most controversial aspects of the use of animals in science is the production of
pain. Pain is a central ethical concern. The activation of neural pathways involved in the pain …

[HTML][HTML] Revolutionizing orofacial pain management: the promising potential of stem cell therapy

K Ren, R Vickers, J Murillo… - Frontiers in Pain Research, 2023 - ncbi.nlm.nih.gov
Orofacial pain remains a significant health issue in the United States. Pain originating from
the orofacial region can be composed of a complex array of unique target tissue that …

[HTML][HTML] TRPV1 and TRPV1-expressing nociceptors mediate orofacial pain behaviors in a mouse model of orthodontic tooth movement

S Wang, M Kim, Z Ali, K Ong, EK Pae… - Frontiers in …, 2019 - frontiersin.org
Orthodontic force produces mechanical irritation and inflammation in the periodontium,
which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic …

[HTML][HTML] Preclinical models of deep craniofacial nociception and temporomandibular disorder pain

K Okamoto, M Hasegawa, K Piriyaprasath… - … Dental Science Review, 2021 - Elsevier
Chronic pain in temporomandibular disorder (TMD) is a common health problem.
Cumulating evidence indicates that the etiology of TMD pain is complex with multifactorial …

Effects of stress contagion on anxiogenic‐and orofacial inflammatory pain‐like behaviors with brain activation in mice

K Piriyaprasath, M Hasegawa… - European Journal of …, 2023 - Wiley Online Library
The conditions of stress contagion are induced in bystanders without direct experiences of
stressful events. This study determined the effects of stress contagion on masseter muscle …