Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

E Rossi, R La Rosa, JA Bartell, RL Marvig… - Nature Reviews …, 2021 - nature.com
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat

SP Diggle, M Whiteley - Microbiology, 2020 - microbiologyresearch.org
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen and a model
bacterium for studying virulence and bacterial social traits. While it can be isolated in low …

Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Pangenomics comes of age: from bacteria to plant and animal applications

AA Golicz, PE Bayer, PL Bhalla, J Batley, D Edwards - Trends in Genetics, 2020 - cell.com
The pangenome refers to a collection of genomic sequence found in the entire species or
population rather than in a single individual; the sequence can be core, present in all …

Genomic and Metabolic Characteristics of the Pathogenicity in Pseudomonas aeruginosa

T De Sousa, M Hébraud, MLNE Dapkevicius… - International journal of …, 2021 - mdpi.com
In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas

J Lalucat, M Mulet, M Gomila, E García-Valdés - Genes, 2020 - mdpi.com
The introduction of genomics is profoundly changing current bacterial taxonomy.
Phylogenomics provides accurate methods for delineating species and allows us to infer the …

[HTML][HTML] Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review

A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa is a ubiquitous, motile, gram-negative bacterium that has been
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …

Commensal Pseudomonas strains facilitate protective response against pathogens in the host plant

O Shalev, TL Karasov, DS Lundberg… - Nature ecology & …, 2022 - nature.com
The community structure in the plant-associated microbiome depends collectively on host–
microbe, microbe–microbe and host–microbe–microbe interactions. The ensemble of …

Application of a quantitative framework to improve the accuracy of a bacterial infection model

GR Lewin, A Kapur, DM Cornforth… - Proceedings of the …, 2023 - National Acad Sciences
Laboratory models are critical to basic and translational microbiology research. Models
serve multiple purposes, from providing tractable systems to study cell biology to allowing …