Variable DNA topology is an epigenetic generator of physiological heterogeneity in bacterial populations

CJ Dorman - Molecular Microbiology, 2023 - Wiley Online Library
Transcription is a noisy and stochastic process that produces sibling‐to‐sibling variations in
physiology across a population of genetically identical cells. This pattern of diversity reflects …

Evolution of YacG to safeguard DNA gyrase from external perturbation

P Biswas, S Sengupta, V Nagaraja - Research in Microbiology, 2023 - Elsevier
Cells have evolved strategies to safeguard their genome integrity. We describe a
mechanism to counter double strand breaks in the chromosome that involves the protection …