Background Docetaxel (DTX) has been used to treat numerous types of cancers. It's poor
solubility, serious side effects, and multi-drug resistance (MDR) limits its use in cancer …

It can be foreseen that in a future scenario of malaria eradication, a varied armamentarium
will be required, including strategies for the targeted administration of antimalarial …

We have developed a nanocarrier drug-delivery system based on micelles formed by a new
class of well-defined linear PEGylated two-arm oligomer of cholic acids in aqueous solution …

Angiogenesis plays an essential role in the progression of rheumatoid arthritis (RA). RGD
peptide shows high affinity and selectivity for integrin α v β 3, which is one of the most …

Polymeric micelles have been widely explored preclinically as suitable delivery systems for
poorly soluble chemotherapeutic drugs in cancer therapy. The present study reported the …

In this work, novel docetaxel (DTX)-loaded Tween 80-free Pluronic P123 (P123) micelles
with improved therapeutic effect were developed. The freeze-dried DTX-loaded P123 …

Optimization is a critical process in the development of nanoparticles to apprehend the
formulation variables and quality attributes. The purpose of this study was to evaluate the …

Malignant neoplasms are one of the main causes of death, especially in children, on a
global scale, despite strenuous efforts made at advancing both diagnostic and therapeutic …

Galangin possess wide range of pharmacological activities including antiarthritic,
hepatoprotective, anti-inflammatory, antibacterial, and anticancer especially in …

The aim of this work was to investigate the anti-tumor effect of paclitaxel (PTX)-loaded
methoxy poly (ethylene glycol)-poly (ɛ-caprolactone) nanoparticles (MPEG-NP/PTX) against …