Background—It is recognized that inflammation is an underlying cause of dry eye disease
(DED), with cytokine release involved. We systematically reviewed literature with meta …

Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

Purpose: The objective of the study was to investigate efficacy and mechanisms of mouse
adipose-derived mesenchymal stem cell-derived exosomes (mADSC-Exos) in the …

Investigating cytokines in tear fluid and saliva may offer valuable information for
understanding the pathogenesis of primary Sjögren's syndrome (pSS). Cytokine profiles in …

The conjunctiva is a goblet cell rich mucosal tissue. Goblet cells are supported by tear
growth factors and IL-13 produced by resident immune cells. Goblet cell secretions are …

Validated biomarkers to be used as biological tools for managing ocular surface diseases
(OSDs) are still an unmet need in daily clinical practice. Many studies have contributed to …

The purpose of this study was to analyze inflammation-and pain-related molecules in tears
of patients suffering from chronic ocular pain associated with dry eye (DE) and/or a previous …

We evaluated how different degrees of air pollution affect the ocular surface of a cohort of
human subjects in Beijing by correlating in-patient test outcomes with tear cytokines. A cross …

Sjogren's syndrome (SS) is an autoimmune disease whose pathogenesis is characterized
by an exacerbated T cell infiltration in exocrine glands, markedly associated to the …

Purpose To compare the levels of inflammatory molecules in tear samples between patients
with meibomian gland dysfunction (MGD)-related evaporative dry eye (EDE) and healthy …