Harnessing immune cells to eliminate HIV reservoirs
P Grasberger, AR Sondrini… - Current Opinion in HIV …, 2024 - journals.lww.com
Several studies have shown promise in many preclinical models of disease, including
simian immunodeficiency virus (SIV)/SHIV infection in nonhuman primates and HIV infection …
simian immunodeficiency virus (SIV)/SHIV infection in nonhuman primates and HIV infection …
[HTML][HTML] Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17 …
S Sugawara, B Hueber, G Woolley, K Terry… - Plos …, 2023 - journals.plos.org
Despite their importance, natural killer (NK) cell responses are frequently dysfunctional
during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) …
during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) …
[HTML][HTML] Making a Monkey out of Human Immunodeficiency Virus/Simian Immunodeficiency Virus Pathogenesis: Immune Cell Depletion Experiments as a Tool to …
J Symmonds, T Gaufin, C Xu, KD Raehtz, RM Ribeiro… - Viruses, 2024 - mdpi.com
Understanding the underlying mechanisms of HIV pathogenesis is critical for designing
successful HIV vaccines and cure strategies. However, achieving this goal is complicated by …
successful HIV vaccines and cure strategies. However, achieving this goal is complicated by …
Knockdowns of CD3zeta Chain in Primary NK Cells Illustrate Modulation of Antibody-Dependent Cellular Cytotoxicity Against Human Immunodeficiency Virus-1
S Sugawara, E Lee, MA Craemer, A Pruitt… - AIDS Research and …, 2024 - liebertpub.com
Multifaceted natural killer (NK) cell activities are indispensable for controlling human
immunodeficiency virus (HIV)-1 transmission and pathogenesis. Among the diverse …
immunodeficiency virus (HIV)-1 transmission and pathogenesis. Among the diverse …
NK cells are critical for in vivo control of SARS-CoV-2 replication and suppression of lung damage
RK Reeves, H Balachandran, K Kroll, K Terry… - 2023 - researchsquare.com
Natural killer (NK) cells play a critical role in virus control. However, it has remained largely
unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic …
unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic …
Determinants of Human Immunodeficiency Virus Plasma Viremia
AA Capoferri - 2023 - search.proquest.com
Abstract The Human Immunodeficiency Virus Type 1 (HIV-1) pandemic has resulted in 36.3
million deaths to date. In 2022, 39 million people were living with HIV (PLWH) worldwide …
million deaths to date. In 2022, 39 million people were living with HIV (PLWH) worldwide …
[图书][B] Using Molecularly Barcoded Pathogens and Whole-genome Sequence Data to Understand Host Responses to SIV and Mycobacterium Tuberculosis Infection
RV Moriarty - 2023 - search.proquest.com
Despite extensive research spanning decades, human immunodeficiency virus (HIV) and
Tuberculosis (TB) cause significant morbidity and mortality worldwide. The mechanisms …
Tuberculosis (TB) cause significant morbidity and mortality worldwide. The mechanisms …
[图书][B] Evaluating Immune Responses to Therapeutic Vaccination and Correlates of Post-treatment Control in SIV+ Mauritian Cynomolgus Macaques
OE Harwood - 2023 - search.proquest.com
HIV remains a global health threat that affects millions of individuals worldwide. Antiretroviral
therapy (ART) is effective at suppressing virus replication. Because ART cannot eradicate …
therapy (ART) is effective at suppressing virus replication. Because ART cannot eradicate …
[图书][B] Evaluating the Impact of Antibody Epitope and Function on HIV-1 Vertical Transmission
ZA Yaffe - 2023 - search.proquest.com
Despite significant advances in scientific research and the advent of treatment and
prevention strategies over the past several decades, the HIV/AIDS pandemic continues to …
prevention strategies over the past several decades, the HIV/AIDS pandemic continues to …