Vaccine adjuvant formulations: a pharmaceutical perspective

LA Brito, P Malyala, DT O'Hagan - Seminars in immunology, 2013 - Elsevier
Abstract Formulation science is an unappreciated and often overlooked aspect in the field of
vaccinology. In this review we highlight key attributes necessary to generate well …

Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route

H Choudhury, B Gorain, B Chatterjee… - Current …, 2017 - ingentaconnect.com
Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

Essential role for autophagy in the maintenance of immunological memory against influenza infection

M Chen, MJ Hong, H Sun, L Wang, X Shi, BE Gilbert… - Nature medicine, 2014 - nature.com
Vaccination has been the most widely used strategy to protect against viral infections for
centuries. However, the molecular mechanisms governing the long-term persistence of …

Intranasal nanoparticulate systems as alternative route of drug delivery

A Alshweiat, R Ambrus, II Csóka - Current medicinal chemistry, 2019 - ingentaconnect.com
There is always a need for alternative and efficient methods of drug delivery. The nasal
cavity can be considered as a non-invasive and efficient route of administration. It has been …

Nanomaterial-based delivery of vaccine through nasal route: opportunities, challenges, advantages, and limitations

M Kumar, R Dogra, UK Mandal - Journal of Drug Delivery Science and …, 2022 - Elsevier
Mucosal administration especially via the nasal route is a novel and promising technique for
medication and vaccine delivery. Mucosal pathways provide notable benefits that promote …

Possible triggering effect of influenza vaccination on psoriasis

AT Gunes, E Fetil, S Akarsu… - Journal of …, 2015 - Wiley Online Library
Psoriasis is a chronic, recurrent, immune‐mediated inflammatory disease and it can be
provoked or exacerbated by a variety of different environmental factors, particularly …

New‐onset and exacerbations of psoriasis after mRNA COVID‐19 vaccines: two sides of the same coin?

D Pesqué, E Lopez‐Trujillo… - Journal of the …, 2022 - Wiley Online Library
With COVID-19 mass vaccination, the spectrum of cutaneous reactions to mRNA COVID-19
vaccines described is increasing. 1 While some of these clinical pictures are believed to …

Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in …

AS Madhun, LR Haaheim, JK Nøstbakken, T Ebensen… - Vaccine, 2011 - Elsevier
Vaccination is the best available measure of limiting the impact of the next influenza
pandemic. Ideally, a candidate pandemic influenza vaccine should be easy to administer …

Nasal vaccine delivery

M Ramvikas, M Arumugam, SR Chakrabarti… - … and nanotechnology in …, 2017 - Elsevier
The mucosal surfaces represent the major site of entry of many pathogens, and major
challenges in vaccine development include safety and stability in a suitable dosage form …

[HTML][HTML] Medical applications of nanotechnology

Z Zdrojewicz, M Waracki, B Bugaj, D Pypno… - Advances in Hygiene and …, 2015 - phmd.pl
Nanotechnologies are new areas of research focusing on affecting matter at the atomic and
molecular levels. It is beyond doubt that modern medicine can benefit greatly from it; thus …