Executive summary “Depression is a disorder of mood, so mysteriously painful and elusive
in the way it becomes known to the self—to the mediating intellect—as to verge close to …

The current meta-analysis examined the effects of psilocybin in combination with behavioral
interventions on anxiety and depression in samples with elevated symptoms. Across four …

Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

All classes of drug that are prescribed to treat depression are associated with withdrawal
syndromes. SSRI withdrawal syndrome occurs often and can be severe, and might compel …

Studies on psychotropic medications decrease, discontinuation, or switch have uncovered
withdrawal syndromes. The present overview aimed at analyzing the literature to illustrate …

Public Health England exists to protect and improve the nation's health and wellbeing, and
reduce health inequalities. We do this through world-leading science, research, knowledge …

Depression like many diseases is pleiotropic but unlike cancer and Alzheimer's disease for
example, is still largely stigmatized and falls into the dark shadows of human illness. The …

Background Major depressive disorder is estimated by the WHO to affect more than 300
million people globally, making depression the leading cause of disability worldwide …

Adaptation of the brain to the presence of a drug predicts withdrawal on cessation. The
outcome of adaptation is often referred to as 'physical dependence'in pharmacology, as …

Background: Anxiety and depressive disorders are highly prevalent. Patients are
increasingly using medicinal cannabis products to treat these disorders, but little is known …