Neuroinflammation refers to a highly complicated reaction of the central nervous system
(CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

After decades of being overlooked, a recent wave of studies have explored the roles of
microglia in brain health and disease. Microglia perform important physiological functions to …

Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
resting tremor, bradykinesia, rigidity, and postural instability that also includes non-motor …

This review analyzes the role of TNF-α and its increase in biological fluids in mild cognitive
impairment, and Alzheimer's disease (AD). The potential inhibition of TNF-α with …

Neuroimmune and neurodegenerative ailments impose a substantial societal burden.
Neuroimmune disorders involve the intricate regulatory interactions between the immune …

Mood disorders and substance use disorder (SUD) are of immense medical and social
concern. Although significant progress on neuronal involvement in mood and reward …

Background Recent studies have revealed the link between immune activation and
neurodegenerative diseases. Methods By employing meta-analysis, we estimated the …

Ferroptosis is an oxidative form of iron-dependent cell death characterized by the
accumulation of lipid peroxides on membranes. Iron and lipids containing polyunsaturated …

The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …