Dyslipidemia related diseases such as hyperlipidemia and atherosclerosis are the leading
cause of death in humans. While cellular and molecular basis on the pathophysiology of …

Dyslipidemias and atherosclerosis play a pivotal role in cardiovascular risk and disease.
Although some pathophysiological mechanisms underlying these conditions have been …

Metabolic syndrome (MetS) which is caused by obesity and insulin resistance, is well known
for its predictive capability for the risk of type 2 diabetes mellitus and cardiovascular disease …

Metabolic syndrome (MetS) is prevalent in type 2 diabetes (T2D) patients. The comorbidity of
MetS and T2D increases the risk of cardiovascular complications. The aim of the present …

Most existing genome-wide association analyses are cross-sectional, utilizing only
phenotypic data at a single time point, eg baseline. On the other hand, longitudinal studies …

Background Dyslipidemia is a major health problem in China and an important modifiable
cardiovascular disease (CVD) risk factor. This study aimed to describe the prevalence of …

Aims Nutritional and lifestyle interventions can contribute to prevent and treat obesity and its
complications; however, genetic background may influence the success of a therapy. The …

Systemic Fe overload can contribute to abnormal glucose metabolism and the onset of type
2 diabetes (T2D). Although hepcidin is the master regulator of systemic Fe homeostasis, few …

Background The importance of apolipoprotein E (APOE) in lipid and lipoprotein metabolism
is well established. However, the impact of APOE polymorphisms has never been …

Objective Metabolic disturbance of lysophosphatidylcholine (LPC) is related with
dyslipidemia. Therefore, eight single-nucleotide polymorphisms (SNPs) were selected from …