Owing to the degeneracy of the genetic code, a protein sequence can be encoded by many
different synonymous mRNA coding sequences. Synonymous codon usage was once …

Bacterial genomes reflect their adaptation strategies through nucleotide usage trends found
in their chromosome composition. Bacteria, unlike eukaryotes contain a wide range of …

Transcription, mRNA decay, translation and protein degradation are essential processes
during eukaryotic gene expression, but their relative global contributions to steady‐state …

We show that CO2 can be converted by an engineered “Knallgas” bacterium (Cupriavidus
necator) into the terpene α‐humulene. Heterologous expression of the mevalonate pathway …

We developed a bacterial genetic system based on translation of the his operon leader
peptide gene to determine the relative speed at which the ribosome reads single or multiple …

Synonymous rare codons are considered to be sub-optimal for gene expression because
they are translated more slowly than common codons. Yet surprisingly, many protein coding …

Forsythia suspensa is an important medicinal plant and traditionally applied for the treatment
of inflammation, pyrexia, gonorrhea, diabetes, and so on. However, there is limited …

Background Codon usage bias has been widely reported to correlate with GC composition.
However, the quantitative relationship between codon usage bias and GC composition …

A common feature of ribonucleic acids (RNAs) is that they can undergo a variety of chemical
modifications. As nearly all of these chemical modifications result in an increase in the mass …

The genetic code is degenerate. With the exception of two amino acids (Met and Trp), all
other amino acid residues are each encoded by multiple, so-called synonymous codons …