The immunological and metabolic landscape in primary and metastatic liver cancer

X Li, P Ramadori, D Pfister, M Seehawer… - Nature Reviews …, 2021 - nature.com
The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …

[HTML][HTML] Contradictory roles of lipid metabolism in immune response within the tumor microenvironment

W Yu, Q Lei, L Yang, G Qin, S Liu, D Wang… - Journal of hematology & …, 2021 - Springer
Complex interactions between the immune system and tumor cells exist throughout the
initiation and development of cancer. Although the immune system eliminates malignantly …

[HTML][HTML] Knowledge mapping of immunotherapy for hepatocellular carcinoma: a bibliometric study

J Shen, H Shen, L Ke, J Chen, X Dang, B Liu… - Frontiers in …, 2022 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors,
and many patients are diagnosed with advanced disease. The treatment of advanced liver …

[HTML][HTML] Immune-based therapies for hepatocellular carcinoma

DJ Pinato, N Guerra, P Fessas, R Murphy, T Mineo… - Oncogene, 2020 - nature.com
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related death.
The immune-rich contexture of the HCC microenvironment makes this tumour an appealing …

[HTML][HTML] Mesenchymal stem cell therapy for liver disease: full of chances and challenges

X Yang, Y Meng, Z Han, F Ye, L Wei, C Zong - Cell & bioscience, 2020 - Springer
Liver disease is a major health problem that endangers human health worldwide. Currently,
whole organ allograft transplantation is the gold standard for the treatment of end-stage liver …

[HTML][HTML] CAR-T “the living drugs”, immune checkpoint inhibitors, and precision medicine: a new era of cancer therapy

D Liu - Journal of Hematology & Oncology, 2019 - Springer
New advances in the design and manufacture of monoclonal antibodies, bispecific T cell
engagers, and antibody-drug conjugates make the antibody-directed agents more powerful …

[HTML][HTML] Apoptosis, pyroptosis, and ferroptosis conspiringly induce immunosuppressive hepatocellular carcinoma microenvironment and γδ T-cell imbalance

Y Hu, D Chen, M Hong, J Liu, Y Li, J Hao, L Lu… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is highly malignant and prone to metastasize due to the
heterogeneous and immunosuppressive tumor microenvironment (TME). Programmed cell …

Immunotherapies for hepatocellular carcinoma

JKH Liu, AF Irvine, RL Jones, A Samson - Cancer Medicine, 2022 - Wiley Online Library
Cases of hepatocellular carcinoma (HCC) are rapidly rising. This is particularly the case in
the Western world, as a result of increasing rates of chronic liver disease, secondary to …

Highlights in ultrasound-targeted microbubble destruction-mediated gene/drug delivery strategy for treatment of malignancies

H Li, Y Zhang, H Shu, W Lv, C Su, F Nie - International Journal of …, 2022 - Elsevier
Ultrasound is one of the safest and most advanced medical imaging technologies that is
widely used in clinical practice. Ultrasound microbubbles, traditionally used for contrast …

[HTML][HTML] HCC and molecular targeting therapies: Back to the future

L Rinaldi, E Vetrano, B Rinaldi, R Galiero, A Caturano… - Biomedicines, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the leading causes of death from cancer in the
world. Recently, the effectiveness of new antiviral therapies and the HBV vaccine have …