Estrogen is an important sex steroid hormone which serves an important role in the
regulation of a number of biological functions, including regulating bone density, brain …

It is well established that gastrointestinal (GI) cancers are common and devastating diseases
around the world. Despite the significant progress that has been made in the treatment of GI …

In recent years, Bisphenol S (BPS) has increasingly been used as an alternative to
Bisphenol A (BPA) in food, paper, and personal care products. It is imperative to clarify the …

Gender differences in the incidences of cancers have been found in almost all human
cancers. However, the mechanisms that underlie gender disparities in most human cancer …

In a graying world, there is an increasing interest in correlates of aging, especially those
found in early life. Leukocyte telomere length (LTL) is an emerging marker of aging at the …

While early pharmacogenomic studies have primarily been carried out in Western
populations, there has been a notable increase in the number of Asian studies over the past …

Loss of CDH1/Cadherin-1 is a common step towards the acquisition of an abnormal
epithelial phenotype. In gastric cancer (GC), mutation and/or downregulation of …

Background Estrogen receptor (ER) is essential in reproductive development and is also the
primary driver of breast cancers. Deregulation of ER may also be involved in tumorigenesis …

Background Prognosis of gastric cancer (GC) patients with ovarian metastasis (OM) remains
poor. We hereby characterized the role of tumor immune microenvironment (TIME) and …

Abstract Estrogen Receptor 2 (ESR2) is the protein-coding gene of estrogen receptor β
(ERβ) and has been shown to be abundantly expressed in gastric carcinoma (GC) …