The use of polyphenols as adjuvants in lowering risk factors for various debilitating diseases
has been investigated in recent years due to their possible antioxidant action. Polyphenols …

The hypothalamic–pituitary–gonadal axis is of relevance in many processes related to the
development, maturation and ageing of the male. Through this axis, a cascade of …

Aging men display reduced reproductive health; however, testis aging is poorly understood
at the molecular and genomic levels. Here, we utilized single-cell RNA-seq to profile over …

Background: Diabetes reduces semen quality and increasingly occurs during reproductive
years. Diabetes medications, such as metformin, have glucose-independent effects on the …

Infertility affects approximately 15% of the couples wanting to conceive. In 30− 40% of the
cases the aetiology of male infertility remains unknown and is called idiopathic male …

Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …

Cannabis use alters sperm DNA methylation, but the potential reversibility of these changes
is unknown. Semen samples from cannabis users and non-user controls were collected at …

BACKGROUND Infertility affects 15% of men and contributes to nearly half of all cases of
infertility. Infertile men usually have impaired spermatogenesis, presenting as azoospermia …

To evaluate the incidence of apoptosis within the testes of patients who died from severe
acute respiratory syndrome coronavirus 2 (COVID-19) complications, testis tissue was …

MicroRNAs applications were vastly studied throughout the years, spanning from potential
cancer biomarkers to targeted therapies for various diseases. Out of these utilizations, this …