Researches dedicated to reactive oxygen species (ROS) had been performed for decades,
yet the outcomes remain controversial. With the relentless effort of studies, researchers have …

Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …

Summary ARID1A encodes an SWI/SNF chromatin-remodeling factor and is frequently
mutated in various cancers. This study demonstrates that ARID1A-deficient cancer cells are …

The development of effective treatments for cancers requires investigations for a more
detailed and comprehensive understanding of the basic cellular mechanisms involved in …

Oncogene‐induced hyper‐proliferation in cancer cells is accompanied by the onset of
different stresses, including DNA‐replication stress, metabolic stress and oxidative stress …

Cellular reactive oxygen species (ROS) status is stabilized by a balance of ROS generation
and elimination called redox homeostasis. ROS is increased by activation of endoplasmic …

Background Identification of potential novel targets for reversing resistance to Epidermal
Growth Factor Receptor (EGFR)-tyrosine kinase inhibitors (EGFR-TKIs) holds great promise …

Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …