As a lifelong source of neurons, neural stem cells (NSCs) serve multiple crucial functions in
the brain. The senescence of NSCs may be associated with the onset and progression of …

Alzheimer's disease (AD) is associated with reduced adult hippocampal neurogenesis and
impaired hippocampal-dependent behaviors. Li et al. 1 report that stimulating adult …

In our ageing global population, the cognitive decline associated with dementia and
neurodegenerative diseases represents a major healthcare problem. To date, there are no …

Here, we provide an in-depth consideration of our current understanding of engrams,
spanning from molecular to network levels, and hippocampal neurogenesis, in health and …

Major depression is an established risk factor for subsequent dementia, and depression in
late life may also represent a prodromal state of dementia. Considering current challenges …

Hippocampal neurogenesis (HN) occurs throughout the life course and is important for
memory and mood. Declining with age, HN plays a pivotal role in cognitive decline (CD) …

Integrating and analyzing multiple omics data sets, including genomics, proteomics and
radiomics, can significantly advance researchers' comprehensive understanding of …

The intricate interplay of one-carbon metabolism (OCM) with various cellular processes has
garnered substantial attention due to its fundamental implications in several biological …

Context Resveratrol (RV) is a natural compound found in grapes, wine, berries, and peanuts
and has potential health benefits—namely, neurogenesis improvement. Neurogenesis …

Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two common diseases
that affect the elderly population worldwide. The identification of common genes associated …