Cholinergic receptors represent a promising class of diagnostic and therapeutic targets due
to their significant involvement in cognitive decline associated with neurological disorders …

Introduction Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental
disorder affecting up to 5.3% of children and 2.5% of adults depending on the country …

Acetylcholine-binding proteins (AChBPs) from mollusks are suitable structural and functional
surrogates of the nicotinic acetylcholine receptors when combined with transmembrane …

Attention deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed
neurobehavioral disorder in children and adolescents, and in about half of these patients …

The growing interest in nicotinic receptors, because of their wide expression in neuronal and
non‐neuronal tissues and their involvement in several important CNS pathologies, has …

Nicotinic acetylcholine receptor (nAChR) α4 and β2 subunits assemble in two alternate
stoichiometries to produce (α4β2) 2 α4 and (α4β2) 2 β2, which display different agonist …

Reciprocal interactions between glia and neurons are essential for many critical functions in
brain health and disease. Microglial cells, the brain resident macrophages, and astrocytes …

An increasing body of evidence has implicated the central muscarinic system as contributing
to a number of symptoms of schizophrenia and serving as a potential target for …

αO-Conotoxin GeXIVA is a selective α9α10 nicotinic acetylcholine receptor (nAChR)
inhibitor displaying two disulfide bonds that can form three isomers. The bead (GeXIVA [1 …

Glioblastomas (GBMs), the most frequent and aggressive human primary brain tumours,
have altered cell metabolism, and one of the strongest indicators of malignancy is an …