Neuroanatomical Substrates of Circuit-Specific Cholinergic Modulation across the Primate Anterior Cingulate Cortex

A Tsolias, Y Zhou, CA Mojica, M Sakharkar… - Journal of …, 2024 - Soc Neuroscience
Acetylcholine is a robust neuromodulator of the limbic system and a critical regulator of
arousal and emotions. The anterior cingulate cortex (ACC) and the amygdala (AMY) are key …

[HTML][HTML] Comparison between human and rodent neurons for persistent activity performance: A biologically plausible computational investigation

Q Zhang, Y Zeng, T Zhang, T Yang - Frontiers in systems …, 2021 - frontiersin.org
Elucidating the multi-scale detailed differences between the human brain and other brains
will help shed light on what makes us unique as a species. Computational models help link …

[HTML][HTML] Functional Constructivism Approach to Multilevel Nature of Bio-Behavioral Diversity

I Trofimova - Frontiers in Psychiatry, 2021 - frontiersin.org
Attempts to revise the existing classifications of psychiatric disorders (DSM and ICD)
continue and highlight a crucial need for the identification of biomarkers underlying …

[HTML][HTML] Desensitizing nicotinic agents normalize tinnitus-related inhibitory dysfunction in the auditory cortex and ameliorate behavioral evidence of tinnitus

M Ghimire, R Cai, L Ling, KA Brownell… - Frontiers in …, 2023 - frontiersin.org
Tinnitus impacts between 10–20% of the population. Individuals most troubled by their
tinnitus have their attention bound to and are distracted by, their tinnitus percept. While …

Chrna5 is essential for a rapid and protected response to optogenetic release of endogenous acetylcholine in prefrontal cortex

S Venkatesan, EK Lambe - Journal of Neuroscience, 2020 - Soc Neuroscience
Optimal attention performance requires cholinergic modulation of corticothalamic neurons in
the prefrontal cortex. These pyramidal cells express specialized nicotinic acetylcholine …

Cortical VIP+/ChAT+ interneurons: From genetics to function

A Dudai, N Yayon, H Soreq… - Journal of …, 2021 - Wiley Online Library
One of the urgent tasks of neuroscience is to understand how neuronal circuits operate,
what makes them fail, and how to repair them when needed. Achieving this goal requires …

Phasic cholinergic signaling promotes emergence of local gamma rhythms in excitatory–inhibitory networks

Y Lu, M Sarter, M Zochowski… - European Journal of …, 2020 - Wiley Online Library
Recent experimental results have shown that the detection of cues in behavioral attention
tasks relies on transient increases of acetylcholine (ACh) release in frontal cortex and …

[HTML][HTML] Niveles de colinesterasa sérica en agricultores de San Pablo de Borbur, Boyacá, expuestos a organofosforados

AF Rodríguez-Gil, EX Urbano-Cáceres… - Revista de la …, 2023 - scielo.org.co
Objetivo: Determinar los niveles de colinesterasa sérica y factores relacionados con la
exposición a organofosforados en agricultores de la vereda de Páramo Lagunas de San …

Putative neurochemical and cell type contributions to hemodynamic activity in the rodent caudate putamen

BM Katz, LR Walton, KM Houston… - Journal of Cerebral …, 2023 - journals.sagepub.com
Functional magnetic resonance imaging (fMRI) is widely used by researchers to
noninvasively monitor brain-wide activity. The traditional assumption of a uniform …

[HTML][HTML] Combining hypothesis-and data-driven neuroscience modeling in FAIR workflows

O Eriksson, US Bhalla, KT Blackwell, SM Crook… - Elife, 2022 - elifesciences.org
Modeling in neuroscience occurs at the intersection of different points of view and
approaches. Typically, hypothesis-driven modeling brings a question into focus so that a …