Pharmacology and therapeutics of bronchodilators

M Cazzola, CP Page, L Calzetta, MG Matera - Pharmacological Reviews, 2012 - ASPET
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …

β2-Agonist Therapy in Lung Disease

M Cazzola, CP Page, P Rogliani… - American journal of …, 2013 - atsjournals.org
β2-Agonists are effective bronchodilators due primarily to their ability to relax airway smooth
muscle (ASM). They exert their effects via their binding to the active site of β2-adrenoceptors …

Leitlinie zur Diagnostik und Therapie von Patienten mit chronisch obstruktiver Bronchitis und Lungenemphysem (COPD)

C Vogelmeier, R Buhl, O Burghuber, CP Criée… - …, 2018 - thieme-connect.com
Das vorliegende Dokument ist eine Neufassung und Aktualisierung der Leitlinie zur
Diagnostik und Therapie von Patienten mit COPD, die die bisherige Version aus dem Jahr …

Comparisons of health status scores with MRC grades in COPD: implications for the GOLD 2011 classification

PW Jones, L Adamek, G Nadeau… - European Respiratory …, 2013 - Eur Respiratory Soc
The 2011 Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy document
recommends assessment of chronic obstructive pulmonary disease (COPD) using …

Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD

D Price, B Yawn, G Brusselle, A Rossi - Primary Care Respiratory …, 2013 - nature.com
While the pharmacological management of chronic obstructive pulmonary disease (COPD)
has evolved from the drugs used to treat asthma, the treatment models are different and the …

Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

KM Kew, S Dias, CJ Cates - Cochrane Database of Systematic …, 2014 - cochranelibrary.com
Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a
network meta‐analysis - Kew, KM - 2014 | Cochrane Library Skip to Content Cookies Our site …

β2‐adrenoceptor agonists: current and future direction

M Cazzola, L Calzetta… - British journal of …, 2011 - Wiley Online Library
Despite the passionate debate over the use of β2‐adrenoceptor agonists in the treatment of
airway disorders, these agents are still central in the symptomatic management of asthma …

Concurrent use of indacaterol plus tiotropium in patients with COPD provides superior bronchodilation compared with tiotropium alone: a randomised, double-blind …

DA Mahler, A D'Urzo, ED Bateman, SA Özkan, T White… - Thorax, 2012 - thorax.bmj.com
Background Current guidelines recommend treatment with one or more long-acting
bronchodilators for patients with moderate or more severe chronic obstructive pulmonary …

The St. George's Respiratory Questionnaire as a prognostic factor in IPF

T Furukawa, H Taniguchi, M Ando, Y Kondoh… - Respiratory …, 2017 - Springer
Background It is unclear whether health related quality of life (HRQL) may have a predictive
value for mortality in idiopathic pulmonary fibrosis (IPF). We investigated the relationship …

Safety and tolerability of once-daily umeclidinium/vilanterol 125/25 mcg and umeclidinium 125 mcg in patients with chronic obstructive pulmonary disease: results …

JF Donohue, D Niewoehner, J Brooks, D O'Dell… - Respiratory …, 2014 - Springer
Background The long-acting muscarinic antagonist (LAMA) umeclidinium (UMEC) and the
combination of UMEC with the long-acting β 2-agonist (LABA) vilanterol (UMEC/VI) are …