Biomaterials and advanced technologies for hemostatic management of bleeding
DSA Hickman, CL Pawlowski, UDS Sekhon… - Advanced …, 2018 - Wiley Online Library
Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …
associated, or drug‐induced blood disorders can cause significant morbidities and …
Protein lipidation: occurrence, mechanisms, biological functions, and enabling technologies
Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia
N Scott‐Hewitt, F Perrucci, R Morini, M Erreni… - The EMBO …, 2020 - embopress.org
Neuronal circuit assembly requires the fine balance between synapse formation and
elimination. Microglia, through the elimination of supernumerary synapses, have an …
elimination. Microglia, through the elimination of supernumerary synapses, have an …
Immunological and toxicological considerations for the design of liposomes
Liposomes hold great potential as gene and drug delivery vehicles due to their
biocompatibility and modular properties, coupled with the major advantage of attenuating …
biocompatibility and modular properties, coupled with the major advantage of attenuating …
COVID-19-associated coagulopathy: an exacerbated immunothrombosis response
A Jayarangaiah, PT Kariyanna… - Clinical and Applied …, 2020 - journals.sagepub.com
Since the onset of the global pandemic in early 2020, coronavirus disease 2019 (COVID-19)
has posed a multitude of challenges to health care systems worldwide. In order to combat …
has posed a multitude of challenges to health care systems worldwide. In order to combat …
[HTML][HTML] A review on phospholipids and their main applications in drug delivery systems
J Li, X Wang, T Zhang, C Wang, Z Huang, X Luo… - Asian journal of …, 2015 - Elsevier
Phospholipids have the characteristics of excellent biocompatibility and a especial
amphiphilicity. These unique properties make phospholipids most appropriate to be …
amphiphilicity. These unique properties make phospholipids most appropriate to be …
[HTML][HTML] The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases
L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
Thrombosis as an intravascular effector of innate immunity
B Engelmann, S Massberg - Nature Reviews Immunology, 2013 - nature.com
Thrombosis is the most frequent cause of mortality worldwide and is closely linked to
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …
[HTML][HTML] P4-ATPases as phospholipid flippases—structure, function, and enigmas
JP Andersen, AL Vestergaard, SA Mikkelsen… - Frontiers in …, 2016 - frontiersin.org
P4-ATPases comprise a family of P-type ATPases that actively transport or flip phospholipids
across cell membranes. This generates and maintains membrane lipid asymmetry, a …
across cell membranes. This generates and maintains membrane lipid asymmetry, a …
The use of natural and synthetic phospholipids as pharmaceutical excipients
P Van Hoogevest, A Wendel - European journal of lipid science …, 2014 - Wiley Online Library
In pharmaceutical formulations, phospholipids obtained from plant or animal sources and
synthetic phospholipids are used. Natural phospholipids are purified from, eg, soybeans or …
synthetic phospholipids are used. Natural phospholipids are purified from, eg, soybeans or …