Glucocorticoid therapy is widely used, but withdrawal from glucocorticoids comes with a
potential life-threatening risk of adrenal insufficiency. Recent case reports document that …

Despite the availability of several formulations of inhaled corticosteroids (ICS) and delivery
devices for treatment of childhood asthma and despite the development of evidence-based …

The application of large-scale metabolomic profiling provides new opportunities for realizing
the potential of omics-based precision medicine for asthma. By leveraging data from over …

Context: Central hypoadrenalism is a frequent complication of pituitary and hypothalamic
pathology and is associated with increased morbidity and mortality. Optimal exogenous …

Glucocorticoids are, besides non-steroidal anti-inflammatory drugs, the most widely used
anti-inflammatory medications. Prevalence studies indicate substantial use of both systemic …

Background Inhaled corticosteroids (ICS) are the most effective treatment for children with
persistent asthma. However adverse effects of ICS on Hypothalamo Pituitary Adrenal (HPA) …

Glucocorticoids (GC s) are steroid hormones, which are essential for life. They are secreted
by the adrenal cortex under the control of the hypothalamic‐pituitary‐adrenal (HPA) axis …

Background Adrenal suppression (AS) is an under-recognised side effect of glucocorticoid
(GC) use. AS may go undetected until a physiological stress precipitates an adrenal crisis …

Inhaled corticosteroids (ICS) have been used as first line treatment of asthma for many
decades. ICS are a form of exogenous glucocorticosteroids that can suppress the …

Inhaled corticosteroids (ICS) are drugs of choice for persistent asthma. Less than 500 µg/d of
fluticasone are believed to be safe. We found 92 cases of adrenal suppression in PubMed; …