[HTML][HTML] Gut microbiota in anxiety and depression: unveiling the relationships and management options

A Kumar, J Pramanik, N Goyal, D Chauhan… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in developing …

Relationship of sleep disorder with neurodegenerative and psychiatric diseases: an updated review

X Xiao, Y Rui, Y Jin, M Chen - Neurochemical Research, 2024 - Springer
Sleep disorders affect many people worldwide and can accompany neurodegenerative and
psychiatric diseases. Sleep may be altered before the clinical manifestations of some of …

[HTML][HTML] The metaverse as a virtual model of platform urbanism: its converging AIoT, XReality, neurotech, and nanobiotech and their applications, challenges, and …

SE Bibri - Smart Cities, 2023 - mdpi.com
With their exponentially rising computational power, digital platforms are heralding a new
era of hybrid intelligence. There has recently been much enthusiasm and hype that the …

[HTML][HTML] The connexin hemichannel inhibitor D4 produces rapid antidepressant-like effects in mice

H Li, A Guo, M Salgado, JC Sáez, CG Lau - Journal of Neuroinflammation, 2023 - Springer
Depression is a common mood disorder characterized by a range of clinical symptoms,
including prolonged low mood and diminished interest. Although many clinical and animal …

[HTML][HTML] Bacopaside I alleviates depressive-like behaviors by modulating the gut microbiome and host metabolism in CUMS-induced mice

J Wang, J Xin, X Xu, W Chen, Y Lv, Y Wei, X Wei… - Biomedicine & …, 2024 - Elsevier
Bacopaside I (BSI) is a natural compound that is difficult to absorb orally but has been
shown to have antidepressant effects. The microbiota-gut-brain axis is involved in the …

Associations between metabolic syndrome and anxiety, and the mediating role of inflammation: Findings from the UK Biobank

M Cen, L Song, X Fu, X Gao, Q Zuo, J Wu - Brain, Behavior, and Immunity, 2024 - Elsevier
Objectives To investigate the association between metabolic syndrome (MetS) and anxiety
and to explore the mediating role of inflammation indicators in this relationship based on the …

Associations between urinary heavy metals and anxiety among adults in the National Health and Nutrition Examination Survey (NHANES), 2007–2012

J Gui, R Ding, D Huang, L Wang, Z Han, X Yang… - Chemosphere, 2023 - Elsevier
Background Few studies have investigated the associations between heavy metals and
anxiety. The purpose of this study was to examine the associations between single and …

NEDD4 Like E3 Ubiquitin Protein Ligase Represses Astrocyte Activation and Aggravates Neuroinflammation in Mice with Depression via Paired Box 6 Ubiquitination

X Wang, M Su, L Wang, Y Zhou, N Li, B Yang - Neuroscience, 2023 - Elsevier
Astrocytes are implicated in stress-induced neuroinflammatory responses in depression.
This paper was to explore the molecular mechanism of the E3 ubiquitin ligase NEDD4L …

Areca Thirteen Pill Improves Depression in Rat by Modulation of the Chemokine/Chemokine Receptor Axis

J Bai, M Ao, A Xing, L Yu, H Tong, W Bao… - Molecular …, 2023 - Springer
Depressive disorder is a severe and complex mental illness. There are a few anti-
depressive medications that can reduce depressive symptoms, but with adverse or side …

[HTML][HTML] Thirty Risk Factors for Alzheimer's Disease Unified by a Common Neuroimmune–Neuroinflammation Mechanism

DF Weaver - Brain Sciences, 2023 - mdpi.com
One of the major obstacles confronting the formulation of a mechanistic understanding for
Alzheimer's disease (AD) is its immense complexity—a complexity that traverses the full …