[HTML][HTML] Chemokines and chemokine receptors: orchestrating tumor metastasization

E Marcuzzi, R Angioni, B Molon, B Calì - International journal of molecular …, 2018 - mdpi.com
Metastasis still represents the primary cause of cancer morbidity and mortality worldwide.
Chemokine signalling contributes to the overall process of cancer growth and metastasis …

Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment

M O'Hayre, CL Salanga, TM Handel… - Biochemical …, 2008 - portlandpress.com
Inappropriate chemokine/receptor expression or regulation is linked to many diseases,
especially those characterized by an excessive cellular infiltrate, such as rheumatoid arthritis …

[图书][B] Multiscale modeling of cancer: an integrated experimental and mathematical modeling approach

V Cristini, J Lowengrub - 2010 - books.google.com
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …

Chemokine receptors in cancer metastasis and cancer cell‐derived chemokines in host immune response

K Koizumi, S Hojo, T Akashi, K Yasumoto… - Cancer science, 2007 - Wiley Online Library
The chemotactic cytokines called chemokines are a superfamily of small secreted cytokines
that were initially characterized through their ability to prompt the migration of leukocytes …

[HTML][HTML] Chemokine receptor-specific antibodies in cancer immunotherapy: achievements and challenges

M Vela, M Aris, M Llorente, JA Garcia-Sanz… - Frontiers in …, 2015 - frontiersin.org
The 1990s brought a burst of information regarding the structure, expression pattern, and
role in leukocyte migration and adhesion of chemokines and their receptors. At that time, the …

The chemokine CXCL8 in carcinogenesis and drug response

D Gales, C Clark, U Manne… - International Scholarly …, 2013 - Wiley Online Library
Although the functions of chemokines in the regulation of immune processes have been
studied in some detail, the role of these biomolecules in cancer is not fully understood …

Inflammation and cancer: the oncogene-driven connection

MG Borrello, D Degl'Innocenti, MA Pierotti - Cancer letters, 2008 - Elsevier
Inflammation has long been suspected to contribute to tumor growth. However, the concept
that the oncogenes, known for decades as responsible for cell neoplastic transformation …

Systematic analysis of chemokines reveals CCL18 is a prognostic biomarker in glioblastoma

W Gao, Y Li, T Zhang, J Lu, J Pan, Q Qi… - Journal of …, 2022 - Taylor & Francis
Background Glioblastoma (GBM) is the most common and aggressive brain tumor in adults,
in which chemokines are often upregulated and may play pivotal roles in their development …

Mesenchymal stem cell-derived CCL-9 and CCL-5 promote mammary tumor cell invasion and the activation of matrix metalloproteinases

M Swamydas, K Ricci, SL Rego… - Cell adhesion & …, 2013 - Taylor & Francis
Stromal chemokine gradients within the breast tissue microenvironment play a critical role in
breast cancer cell invasion, a prerequisite to metastasis. To elucidate which chemokines …

Anti-inflammatory agents as cancer therapeutics

K Kashfi - Advances in pharmacology, 2009 - Elsevier
Cancer prevention sometimes referred to as tertiary prevention or chemoprevention makes
use of specific xenobiotics or drugs to prevent, delay, or retard the development of cancer …