Association of vitamin D metabolism gene polymorphisms with autoimmunity: evidence in population genetic studies

AI Ruiz-Ballesteros, MR Meza-Meza… - International journal of …, 2020 - mdpi.com
A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

[HTML][HTML] A review of the critical role of vitamin D axis on the immune system

G Daryabor, N Gholijani, FR Kahmini - Experimental and Molecular …, 2023 - Elsevier
In recent years, the physiological and molecular functions of vitamin D (Vit-D) have been
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …

VDR polymorphisms in autoimmune connective tissue diseases: focus on Italian population

A Latini, G De Benedittis, C Perricone… - Journal of …, 2021 - Wiley Online Library
Vitamin D is an important hormone involved in various physiologic processes, and its activity
is linked to binding with vitamin D receptor (VDR). Genetic polymorphisms in the VDR gene …

Vitamin D Receptor (VDR) Genetic Variants: Relationship of FokI Genotypes with VDR Expression and Clinical Disease Activity in Systemic Lupus Erythematosus …

MR Meza-Meza, B Vizmanos, M Rivera-Escoto… - Genes, 2022 - mdpi.com
Vitamin D (VD) deficiency is more frequent in systemic lupus erythematosus (SLE) patients
than in control subjects (CS); genetic variants in the VD receptor (VDR) could contribute to …

Vitamin D in SLE: a role in pathogenesis and fatigue? A review of the literature

MH Nguyen, K Bryant, SG O'Neill - Lupus, 2018 - journals.sagepub.com
Fatigue is a common, disabling problem that is highly prevalent in patients with systemic
lupus erythematous (SLE). More recently, vitamin D status has been established as a …

Vitamin D supplementation increases adipokine concentrations in overweight or obese adults

A Mousa, N Naderpoor, K Wilson, M Plebanski… - European journal of …, 2020 - Springer
Purpose Vitamin D regulates adipokine production in vitro; however, clinical trials have been
inconclusive. We conducted secondary analyses of a randomized controlled trial to examine …

Leveraging machine learning to evaluate factors influencing vitamin D insufficiency in SLE patients: A case study from southern Bangladesh

M Saha, A Deb, I Sultan, S Paul, J Ahmed… - PLOS Global Public …, 2023 - journals.plos.org
Vitamin D insufficiency appears to be prevalent in SLE patients. Multiple factors potentially
contribute to lower vitamin D levels, including limited sun exposure, the use of sunscreen …

Vitamin D status in Hashimoto's thyroiditis and its association with vitamin D receptor genetic variants

HWZ Hanna, C Rizzo, RMA Halim… - The Journal of Steroid …, 2021 - Elsevier
Background Hashimoto's thyroiditis (HT) is considered the predominant cause of
hypothyroidism in iodine sufficient countries. The deficiency of 25− OH-vitamin D3 serum …

Vitamin D receptor FokI, TaqI, and ApaI polymorphisms and susceptibility to systemic lupus erythematosus: an updated meta-analysis

SC Bae, YH Lee - Clinical Rheumatology, 2018 - Springer
This study aimed to explore whether vitamin D receptor (VDR) polymorphisms are
associated with susceptibility to systemic lupus erythematosus (SLE). Meta-analyses were …

[HTML][HTML] Effect of vitamin D receptor gene polymorphism on lipid profile in Egyptian children with juvenile idiopathic arthritis

SAK Rady, NA Doudar, OE Boutros, MTL Hana… - The Egyptian …, 2022 - Elsevier
Aim of the work To assess the effect of vitamin D receptor (VDR) polymorphism on lipid
profile in patients with juvenile idiopathic arthritis (JIA) and study its relation to disease …