Molecular biomarkers in cancer

VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer

KA Preethi, SC Selvakumar, K Ross, S Jayaraman… - Molecular Cancer, 2022 - Springer
Background Detecting cancer at an early stage before clinical manifestation could be an
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …

Tumor-derived exosomal non-coding RNAs as diagnostic biomarkers in cancer

N Ebrahimi, F Faghihkhorasani, SS Fakhr… - Cellular and Molecular …, 2022 - Springer
Almost all clinical oncologists agree that the discovery of reliable, accessible, and non-
invasive biomarkers is necessary to decrease cancer mortality. It is possible to employ …

A tale of exosomes and their implication in cancer

A Mishra, PS Bharti, N Rani, F Nikolajeff… - Biochimica et Biophysica …, 2023 - Elsevier
Cancer is a cause of high deaths worldwide and also a huge burden for the health system.
Cancer cells have unique properties such as a high rate of proliferation, self-renewal …

The role of mesenchymal stem cells derived exosomes as a novel nanobiotechnology target in the diagnosis and treatment of cancer

Y Zhou, Y Dong, A Zhang, J Wu, Q Sun - Frontiers in Bioengineering …, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs), one of the most common types of stem cells, are involved
in the modulation of the tumor microenvironment (TME). With the advancement of …

Extracellular vesicles and exosomes: novel insights and perspectives on lung cancer from early detection to targeted treatment

S Rahimian, H Najafi, B Afzali, M Doroudian - Biomedicines, 2024 - mdpi.com
Lung cancer demands innovative approaches for early detection and targeted treatment. In
addressing this urgent need, exosomes play a pivotal role in revolutionizing both the early …

Plasma exosomal miR-320d, miR-4479, and miR-6763-5p as diagnostic biomarkers in epithelial ovarian cancer

S Wang, X Song, K Wang, B Zheng, Q Lin, M Yu… - Frontiers in …, 2022 - frontiersin.org
Background Exosomal miRNA had been proved as the promising biomarkers for multiple
cancers including epithelial ovarian cancer (EOC). This study aimed to validate the …

Serum exosomes and their miRNA load—A potential biomarker of lung cancer

M Smolarz, P Widlak - Cancers, 2021 - mdpi.com
Simple Summary Exosomes are an emerging source of cancer biomarkers. Molecular
components of serum-derived exosomes have been addressed in several reports in the …

[HTML][HTML] The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer

Z Wang, W Xie, H Guan - Biomedicine & Pharmacotherapy, 2023 - Elsevier
MicroRNA are non-coding small RNAs that bind to their target mRNA and cause mRNA
degradation or translation inhibition. MiRNA dysregulation is linked to a variety of human …

Extracellular circulating miRNAs as potential non-invasive biomarkers in non-small cell lung cancer patients

J Raczkowska, A Bielska, A Krętowski… - Frontiers in …, 2023 - frontiersin.org
Non-small cell lung cancer (NSCLC) comprises 85% of all lung cancers and is a malignant
condition resistant to advanced-stage treatment. Despite the advancement in detection and …