High-throughput next-generation sequencing now makes it possible to generate a vast
amount of multi-omics data for various applications. These data have revolutionized …

The active form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is primarily
known as a key regulator of calcium and phosphate homeostasis. It exerts its biological …

Breast cancer (BrCa) is the leading cause of cancer incidence and mortality in women
worldwide. While BrCa treatment has been shown to be highly successful if detected at an …

Human epidermal growth factor receptor 2 (HER2) receptor tyrosine kinase is
overexpressed in 20–30% of breast cancers and is associated with poor prognosis and …

Breast cancer clinical treatment selection is based on the immunohistochemical
determination of four protein biomarkers: ESR1, PGR, HER2, and MKI67. Our aim was to …

Simple Summary Internationally, in women, breast cancer (BC) is the most common cancer
type and is the leading cause of cancer-related death. There are two main histological …

Identifying patients likely to develop breast cancer recurrence remains a challenge. Thus,
the discovery of biomarkers capable of diagnosing recurrence is of the utmost importance …

Notch signaling dysregulation encourages breast cancer progression through different
mechanisms such as stem cell maintenance, cell proliferation and migration/invasion …

It is known that estrogen stimulates growth and inhibits apoptosis through estrogen receptor
(ER)-mediated mechanisms in many cancer cell types. Interestingly, there is strong evidence …

Although cannabinoids have been used for centuries for diverse pathological conditions,
recently, their clinical interest and application have emerged due to their diverse …