Combinatorial control of Pseudomonas aeruginosa biofilm development by quorum-sensing and nutrient-sensing regulators

G Chen, G Fanouraki, A Anandhi Rangarajan… - …, 2024 - journals.asm.org
The human pathogen Pseudomonas aeruginosa, a leading cause of hospital-acquired
infections, inhabits and forms sessile antibiotic-resistant communities called biofilms in a …

[HTML][HTML] Loss of LasR function leads to decreased repression of Pseudomonas aeruginosa PhoB activity at physiological phosphate concentrations

A Conaway, I Todorovic, DL Mould, DA Hogan - bioRxiv, 2024 - ncbi.nlm.nih.gov
Abstract While the Pseudomonas aeruginosa LasR transcription factor plays a role in
quorum sensing (QS) across phylogenetically-distinct lineages, isolates with loss-of-function …

Microbial Metabolomics to Understand Antimicrobial Resistance and Drug Metabolism

R Venkataraman, K Nakedi, AS Akhade… - … Resistance: Factors to …, 2024 - Springer
The bacterial metabolome provides a comprehensive profile of the biochemical and
metabolic status within the cell. Gaining a deeper insight into the metabolome has proven to …

Antimicrobial Resistance and Drug

R Venkataraman, K Nakedi, AS Akhade… - … Resistance: Factors to … - books.google.com
At the dawn of the era of molecular biology, a unidirectional flow of information from DNA to
RNA to proteins, which subsequently produced metabolites, was hypothesized. However …

The past, present and future of polymicrobial infection research: Modelling, eavesdropping, terraforming and other stories

ÉB Bényei, RR Nazeer, I Askenasy… - Advances in …, 2024 - pubmed.ncbi.nlm.nih.gov
Over the last two centuries, great advances have been made in microbiology as a discipline.
Much of this progress has come about as a consequence of studying the growth and …