Nicotinamide adenine dinucleotide (NAD+) is indispensable for various oxidation-reduction
reactions in mammalian cells, particularly during energy production. Malignant cells …

Pharmacogenomics (PGx) is the hope for the full optimization of drug therapy while
minimizing the accompanying adverse drug events that cost billions of dollars annually …

Prostate cancer is the second leading cause of noncutaneous cancer-related deaths in
American men. Androgen deprivation therapy (ADT), radical prostatectomy, and …

A reliable suspension-based platform for scaling engineered cardiac tissue (ECT)
production from human induced pluripotent stem cells (hiPSCs) is crucial for regenerative …

Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the biosynthesis of
nicotinamide adenine dinucleotide (NAD+), making it a potential target for cancer therapy …

Neuroendocrine prostate cancer (NEPC) is an aggressive advanced subtype of prostate
cancer that exhibits poor prognosis and broad resistance to therapies. Currently, few …

Introduction Prostate cancer (PC) is the most common malignancy and accounts for a
significant proportion of cancer deaths among men. Although initial therapy success can …

Prostate cancer is a malignant tumor of the male urological system with the highest
incidence rate in the world, which seriously threatens the life and health of middle-aged and …

Multiple myeloma is the second-most common hematopoietic malignancy in the United
States. Although several drugs have so far been approved by the FDA to treat myeloma and …

Drug resistance has remained the Achilles' heel in cancer chemotherapy which serves as
the principal limiting factor in achieving favorable treatment outcomes in cancer patients …