Aging as a loss of morphostatic information: a developmental bioelectricity perspective

L Pio-Lopez, M Levin - Ageing Research Reviews, 2024 - Elsevier
Maintaining order at the tissue level is crucial throughout the lifespan, as failure can lead to
cancer and an accumulation of molecular and cellular disorders. Perhaps, the most …

Inorganic phosphate (Pi) in the breast cancer microenvironment: Production, transport and signal transduction as potential targets for anticancer strategies

MA Lacerda-Abreu… - Current Cancer Drug …, 2023 - ingentaconnect.com
Tumor cells develop a high demand for inorganic phosphate (Pi) due to their high growth
rates and energy requirements. Serum Pi concentrations in cancer patients have been found …

[HTML][HTML] The role of potassium in depth profiling of the tumor border in bone-invasive oral cancer using laser-induced breakdown spectroscopy (LIBS): A pilot study

P Winnand, KO Boernsen, M Ooms, M Heitzer… - Journal of Cancer …, 2023 - Springer
Purpose Microscopic tumor spread beyond the macroscopically visible tumor mass in bone
represents a major risk in surgical oncology, where the spatial complexity of bony resection …

Elemental mapping of human malignant mesothelioma tissue samples using high-speed LA–ICP–TOFMS imaging

OM Voloaca, MR Clench, G Koellensperger… - Analytical …, 2022 - ACS Publications
This is the first report of the use of laser ablation–inductively coupled plasma time-of-flight
mass spectrometry (LA–ICP–TOFMS) to analyze human malignant pleural mesothelioma …

MicroRNA‐497‐5p Is Downregulated in Hepatocellular Carcinoma and Associated with Tumorigenesis and Poor Prognosis in Patients

LL Tian, B Qian, XH Jiang, YS Liu… - … Journal of Genomics, 2021 - Wiley Online Library
Background. MicroRNAs (miRNAs) have been demonstrated to exhibit important regulatory
roles in multiple malignancies, including hepatocellular carcinoma (HCC). hsa‐miR‐497‐5p …

[HTML][HTML] Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo

AM Michaels, A Zoccarato, Z Hoare, G Firth… - Cancer & …, 2024 - Springer
Background Glycolytic flux is regulated by the energy demands of the cell. Upregulated
glycolysis in cancer cells may therefore result from increased demand for adenosine …

[HTML][HTML] Inhibition of Colon Cancer Recurrence via Exogenous TRAIL Delivery Using Gel-like Coacervate Microdroplets

S Kim, Y Jwa, J Hong, K Kim - Gels, 2022 - mdpi.com
Colon cancer (CC) belongs to the three major malignancies with a high recurrence rate.
Therefore, a novel drug delivery system that can prevent CC recurrence while minimizing …

Harnessing the membrane potential to combat cancer progression

M Yang, WJ Brackenbury - Bioelectricity, 2022 - liebertpub.com
Rapid fluctuations in the plasma membrane potential (Vm) provide the basis underlying the
action potential waveform in electrically excitable cells; however, a growing body of literature …

Novel immunotherapeutic approaches to cancer: voltage-gated sodium channel expression in immune cells and tumors

MBA Djamgoz, L Firmenich - Cancer immunology and immunotherapy, 2022 - Elsevier
Although “immunotherapy” is a wonderful concept causing major excitement in cancer
clinics and giving much hope to patients, significant limitations remain in its applications …

A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue

V Juvekar, MK Cho, HW Lee, DJ Lee, H Kang… - Chemical …, 2021 - pubs.rsc.org
A cyclocyanine (CC)-based organic small molecule two-photon (TP) fluorescent probe
(CCNa1) was developed for mitochondrial sodium ion sensing. CCNa1 exhibits a low …