Artificial intelligence and machine learning empower advanced biomedical material design to toxicity prediction

AV Singh, D Rosenkranz, MHD Ansari… - Advanced Intelligent …, 2020 - Wiley Online Library
Materials at the nanoscale exhibit specific physicochemical interactions with their
environment. Therefore, evaluating their toxic potential is a primary requirement for …

[HTML][HTML] Application of Inorganic Nanomaterials in Cultural Heritage Conservation, Risk of Toxicity, and Preventive Measures

LS Gomez-Villalba, C Salcines, R Fort - Nanomaterials, 2023 - mdpi.com
Nanotechnology has allowed for significant progress in architectural, artistic, archaeological,
or museum heritage conservation for repairing and preventing damages produced by …

Importance of Metal Biotransformation in Cell Response to Metallic Nanoparticles: A Transcriptomic Meta-analysis Study

A Balfourier, AP Marty, F Gazeau - ACS Nanoscience Au, 2022 - ACS Publications
Metallic nanoparticles are increasingly present in our environment, raising concerns on their
interactions with living organisms and potential toxicity. Indeed, metallic nanoparticles …

Transcriptomic Integration Analyses Uncover Common Bisphenol A Effects Across Species and Tissues Primarily Mediated by Disruption of JUN/FOS, EGFR, ER …

R Yang, Y Lu, N Yin, F Faiola - Environmental Science & …, 2023 - ACS Publications
Bisphenol A (BPA) is a common endocrine disruptor widely used in the production of
electronic, sports, and medical equipment, as well as consumer products like milk bottles …

[HTML][HTML] Causal biological network model for inflammasome signaling applied for interpreting transcriptomic changes in various inflammatory states

H Yepiskoposyan, MC Peitsch, M Talikka - International Journal of …, 2022 - hindawi.com
Virtually any stressor that alters the cellular homeostatic state may result in an inflammatory
response. As a critical component of innate immunity, inflammasomes play a prominent role …

[HTML][HTML] Causal biological network models for reactive astrogliosis: a systems approach to neuroinflammation

M Barkhuizen, K Renggli, S Gubian, MC Peitsch… - Scientific Reports, 2022 - nature.com
Astrocytes play a central role in the neuroimmune response by responding to CNS
pathologies with diverse molecular and morphological changes during the process of …

Systems Approaches for Toxicological Assessment of Nanomaterials

H Yepiskoposyan, M Talikka, V Belcastro… - …, 2021 - taylorfrancis.com
The 21st-century toxicology paradigm, introduced nearly a decade ago, brought big data
into toxicity testing. Toxicity pathways and signatures derived from high-content assays and …

12 Systems Approaches

H Yepiskoposyan, M Talikka, V Belcastro… - … Toxicity Evaluation of …, 2021 - books.google.com
278 Nanotoxicology from solely using apical endpoints, the 21st-century paradigm shift in
toxicology brought about the idea of toxicity pathways, which are intracellular molecular …