Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

The barrier between the blood and the ventricular cerebrospinal fluid (CSF) is located at the
choroid plexuses. At the interface between two circulating fluids, these richly vascularized …

To maintain the homeostatic environment required for proper function of central nervous
system (CNS) neurons the endothelial cells of CNS microvessels tightly regulate the …

Immune privilege of the central nervous system (CNS) has been ascribed to the presence of
a blood–brain barrier and the lack of lymphatic vessels within the CNS parenchyma …

In multiple sclerosis, brain-reactive T cells invade the central nervous system (CNS) and
induce a self-destructive inflammatory process. T-cell infiltrates are not only found within the …

Multiple sclerosis (MS) is the most common inflammatory disorder of the central nervous
system (CNS) in young adults. When MS is not treated, it leads to irreversible and severe …

Objective To identify and characterize myeloid cell populations within the CSF of patients
with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution …

Recently, a rising interest is given to neuroimmune communication in physiological and
neuropathological conditions. Meningeal immunity is a complex immune environment …

Different immune cell subsets have a relevant role in the pathogenesis of and tissue
damage seen in autoimmune thyroid diseases (AITD), including T regulatory (Treg) …

Dysfunctional immune cells participate in the pathogenesis of a variety of autoimmune
diseases, although the specific mechanisms remain elusive and effective clinical …