Recent update on the heterogeneity of the Alzheimer's disease spectrum

KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia worldwide, is a mixed
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …

[HTML][HTML] Interaction between Alzheimer's disease and cerebral small vessel disease: A review focused on neuroimaging markers

SE Kim, HJ Kim, H Jang, MW Weiner… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is characterized by the presence of β-amyloid (Aβ) and tau, and
subcortical vascular cognitive impairment (SVCI) is characterized by cerebral small vessel …

[HTML][HTML] A meta-analysis of the diagnostic utility of biomarkers in cerebrospinal fluid in Parkinson's disease

C Xiang, S Cong, X Tan, S Ma, Y Liu, H Wang… - npj Parkinson's …, 2022 - nature.com
Biomarkers play important roles in the diagnosis and differential diagnosis of Parkinson's
disease (PD). Thus, we carried out a systematic review and meta-analysis evaluating the …

[HTML][HTML] Neuropathology of the Alzheimer's continuum: An update

KA Jellinger - Free Neuropathology, 2020 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), the most common form of dementia worldwide, is a mixed
proteinopathy (amyloid and tau). Originally defined as a clinicopathological entity, it is a …

Emerging role of vascular burden in AT (N) classification in individuals with Alzheimer's and concomitant cerebrovascular burdens

MY Chun, H Jang, SJ Kim, YH Park, J Yun… - Journal of Neurology …, 2024 - jnnp.bmj.com
Objectives Alzheimer's disease (AD) is characterised by amyloid-beta accumulation (A), tau
aggregation (T) and neurodegeneration (N). Vascular (V) burden has been found …

[HTML][HTML] Alzheimer's Disease and Cognitive Decline in Patients with Cardiovascular Diseases Along the Heart-Brain Axis

C Trieu, AC van Harten, AE Leeuwis… - Journal of …, 2024 - content.iospress.com
Background: We hypothesize that Alzheimer's disease (AD)-related pathology may
accelerate cognitive decline in patients with cardiovascular diseases. Objective: To …

A review of the flortaucipir literature for positron emission tomography imaging of tau neurofibrillary tangles

SC Burnham, L Iaccarino, MJ Pontecorvo… - Brain …, 2024 - academic.oup.com
Alzheimer's disease is defined by the presence of β-amyloid plaques and neurofibrillary tau
tangles potentially preceding clinical symptoms by many years. Previously only detectable …

[HTML][HTML] Total cerebral small vessel disease burden on MRI correlates with medial temporal lobe atrophy and cognitive performance in patients of a memory clinic

Y Fan, M Shen, Y Huo, X Gao, C Li, R Zheng… - Frontiers in Aging …, 2021 - frontiersin.org
Background: Cerebral small vessel disease (cSVD) and neurodegeneration are the two
main causes of dementia and are considered distinct pathological processes, while studies …

[HTML][HTML] White Matter Hyperintensity Volume and Amyloid-PET Synergistically Impact Memory Independent of Tau-PET in Older Adults Without Dementia

L Edwards, KR Thomas, AJ Weigand… - Journal of …, 2023 - content.iospress.com
White Matter Hyperintensity Volume and Amyloid-PET Synergistically Impact Memory
Independent of Tau-PET in Older Adults Without Dementia - IOS Press You are viewing a …

Sleep parameters and plasma biomarkers for cognitive impairment evaluation in patients with cerebral small vessel disease

X Chen, Z Fang, Y Zhao, W Cheng… - The Journals of …, 2023 - academic.oup.com
Objectives Cognitive impairment caused by cerebrovascular disease accounts for more than
half of vascular dementia. However, neuropsychological tests are limited by their …