A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence

T Li, Y Yu, Z Sun, J Duan - Particle and fibre toxicology, 2022 - Springer
The impacts of air pollution on public health have become a great concern worldwide.
Ambient particulate matter (PM) is a major air pollution that comprises a heterogeneous …

[HTML][HTML] The aryl hydrocarbon receptor as a target of environmental stressors–Implications for pollution mediated stress and inflammatory responses

CFA Vogel, LS Van Winkle, C Esser… - Redox biology, 2020 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

Maternal inflammation and its ramifications on fetal neurodevelopment

HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022 - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Fine particulate matter (PM2.5): The culprit for chronic lung diseases in China

T Li, R Hu, Z Chen, Q Li, S Huang, Z Zhu… - Chronic diseases and …, 2018 - mednexus.org
Air pollution is a world public health problem. Particulate matter (PM), a mix of solid and
liquid particles in the air, becomes an increasing concern in the social and economic …

Activation of proinflammatory responses in cells of the airway mucosa by particulate matter: oxidant-and non-oxidant-mediated triggering mechanisms

J Øvrevik, M Refsnes, M Låg, JA Holme, PE Schwarze - Biomolecules, 2015 - mdpi.com
Inflammation is considered to play a central role in a diverse range of disease outcomes
associated with exposure to various types of inhalable particulates. The initial mechanisms …

Does long-term exposure to air pollution impair physical and mental health in the middle-aged and older adults?—A causal empirical analysis based on a longitudinal …

K Ju, L Lu, T Chen, Z Duan, D Chen, W Liao… - Science of the Total …, 2022 - Elsevier
The world is aging, posing a challenge to public health. Air pollution is increasingly
recognized as an important environmental risk factor, with effects on both physical and …

Effects of ambient particulate matter on vascular tissue: a review

K Shkirkova, K Lamorie-Foote, M Connor… - Journal of Toxicology …, 2020 - Taylor & Francis
Fine and ultra-fine particulate matter (PM) are major constituents of urban air pollution and
recognized risk factors for cardiovascular diseases. This review examined the effects of PM …

Selenoprotein P promotes the development of pulmonary arterial hypertension: possible novel therapeutic target

N Kikuchi, K Satoh, R Kurosawa, N Yaoita… - Circulation, 2018 - Am Heart Assoc
Background: Excessive proliferation and apoptosis resistance of pulmonary artery smooth
muscle cells (PASMCs) are key mechanisms of pulmonary arterial hypertension (PAH) …

Exposure of trophoblast cells to fine particulate matter air pollution leads to growth inhibition, inflammation and ER stress

M Familari, Å Nääv, L Erlandsson, RU de Iongh… - PloS one, 2019 - journals.plos.org
Ambient air pollution is considered a major environmental health threat to pregnant women.
Our previous work has shown an association between exposure to airborne particulate …

Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer

C Sweeney, G Lazennec, CFA Vogel - Frontiers in Pharmacology, 2022 - frontiersin.org
Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to
chemicals including polycyclic aromatic hydrocarbons (PAHs) and polychlorinated dibenzo …