Chronic kidney disease (CKD) is a widely diffuse pathological condition which deeply
impacts upon an affected patient's quality of life and its worldwide rate is predicted to further …

Chronic kidney disease (CKD) is characterized by the loss of kidney function. The molecular
mechanisms underlying the development and progression of CKD are still not fully …

Zinc (Zn) is an essential trace element for the body. Studies have confirmed that Zn
deficiency can cause oxidative stress. The purpose of the present study was designed to …

Lysophosphatidic acid (LPA) is a bioactive phospholipid present in most tissues and body
fluids. LPA acts through specific LPA receptors (LPAR1 to LPAR6) coupled with G protein …

Matrix metalloproteinase-7 (MMP-7) is a secreted zinc-dependent endopeptidase that is
implicated in regulating kidney homeostasis and diseases. MMP-7 is produced as an …

Dickkopf-related protein 3 (DKK3) is a secreted glycoprotein that has been implicated in the
pathogenesis of a variety of diseases. Recent evidence suggests that urinary DKK3 may …

Matrix metalloproteinases (MMPs) are a group of zinc and calcium endopeptidases which
cleave extracellular matrix (ECM) proteins. They are also involved in the degradation of cell …

Systemic sclerosis (SSc) is a chronic debilitating idiopathic disorder, characterized by
deposition of excessive extracellular matrix (ECM) proteins such as collagen which leads to …

Metalloproteinases (MPs) are proteolytic enzymes involved in extracellular matrix
deposition, regulation of cellular signals of inflammation, proliferation, and apoptosis …

Deregulated mitochondrial energetics is a metabolic hallmark of cancer cells. However, the
causative mechanism of the bioenergetic deregulation is not clear. In this study, we show …