Background: Renal fibrosis is a key pathological change that occurs in the progression of
almost all chronic kidney diseases. CKD has the characteristics of high morbidity and …

The damage of the endothelial glycocalyx as a consequence of ischemia and/or reperfusion
injury (IRI) following kidney transplantation has come at the spotlight of research due to …

Biomarker development, improvement, and clinical implementation in the context of kidney
disease have been a central focus of biomedical research for decades. To this point, only …

OBJECTIVE The role of fibrosis in early progressive renal decline in type 2 diabetes is
unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix …

Matrix metalloproteinase-7 (MMP-7) has been shown to play important roles in
pathophysiological processes involved in the development/progression of diseases such as …

The traditional chronic kidney disease (CKD) biomarkers (eGFR based on serum creatinine,
sex and age and albuminuria) cannot predict a patient's individual risk for developing …

Objectives To determine if radiological evidence of blood brain barrier (BBB) dysfunction,
measured using Dynamic Contrast Enhanced MRI (DCE-MRI), correlates with serum matrix …

Long-term peritoneal dialysis (PD) causes structural and functional alterations of the
peritoneal membrane. Peritoneal deterioration and fibrosis are multicellular and …

Aims Pulmonary fibrosis seriously affects the health and life quality of patients. Exercise has
been shown to have anti-inflammatory and antioxidant effects, but its effect on pulmonary …

In autoimmune liver disease (AILD), including autoimmune hepatitis (AIH), primary
sclerosing cholangitis (PSC), and overlap syndrome of AIH and PSC (ASC), the presence of …