Chronic kidney disease (CKD) has a very high mortality rate and remains a global health
challenge. Inhibiting renal fibrosis is one of the most promising therapeutic strategies for …

Epithelial-to-mesenchymal transition (EMT) displays a critical role in the development of
renal fibrosis, an important pathological process of chronic kidney disease (CKD) …

Objective Flares of lupus nephritis (LN) are frequent and associated with impaired renal
prognosis. One major management obstacle in LN flare is the lack of effective methods to …

Progression of chronic kidney disease (CKD) portends myriad complications, including
kidney failure. In this study, we analyze associations of 4638 plasma proteins among 3235 …

Chronic kidney disease (CKD) has a worldwide prevalence of higher than 10% with an
increasing mortality rate. As it involves the deterioration of renal function, it represents a …

OBJECTIVE To characterize transcription of profibrotic mediators in renal tissues of cats with
ischemia-induced chronic kidney disease (CKD). SAMPLE Banked renal tissues from 6 cats …

Leishmaniasis, malaria, toxoplasmosis, and acanthamoebiasis are protozoan parasitic
infections. They remain important contributors to the development of kidney disease, which …

Renal ischemia–reperfusion (IR) injury is a common issue in urological surgery, and the
renal tubules, particularly the proximal tubules, are extremely vulnerable to IR injury. In this …

The pathophysiology of Fabry nephropathy (FN) is induced by galactosidase A deficiency
with a chronic exposure of glycolipids to every lineage of renal cells. Tissue damage is …

Chronic kidney disease (CKD) is a slowly progressive condition characterized by decreased
kidney function, tubular injury, oxidative stress, and inflammation. CKD is a leading global …