Avaliação da transição epitélio-mesenquimal em células HK-2 e fibrose renal em modelo murino de infecção por Leptospira interrogans

LG Prado - 2023 - teses.usp.br
A leptospirose é uma zoonose negligenciada distribuída mundialmente, que acomete seres
humanos e animais. A doença clínica é caracterizada por febre, mialgia, cefaleia, injúria …

A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

AM Alchahin, S Mei, I Tsea, T Hirz, Y Kfoury, D Dahl… - bioRxiv, 2022 - biorxiv.org
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer in adults.
When ccRCC is localized to the kidney, surgical resection or ablation of the tumor is often …

Protein ADAMTS-4 kao mogući biološki biljeg kronične bubrežne bolesti

I Kovačević Vojtušek - 2023 - repozitorij.unizg.hr
Sažetak Provedeno je istraživanje pojavnosti ADAMTS-4 proteina u KBB u cilju utvrđivanja
ove molekule kao novog biološkog biljega KBB. Uključeno je 150 ispitanika podijeljenih u 9 …

TGFβ Signaling

AU Trendelenburg - 2020 - books.rsc.org
Fibrosis, a pathological process characterized by excessive accumulation of extracellular
matrix (ECM), contributes to the pathology of a variety of chronic diseases. Fibrosis can …

Biomarkers of acute kidney injury and their role in clinical patient management

EB Deger, E Arslan, MD Deger… - Biomedical Reviews, 2020 - journals.mu-varna.bg
Acute kidney injury (AKI) is a common public health problem and has a significant impact on
cardiovascular disease, mortality and increased hospital costs. Also, AKI can progress to …

The Roles of Matrix Metalloproteinase 7 in Spinal Cord Ischemia-Reperfusion Injury in Rats

T Fang, F Chen, D Wang, Z Zhang - 2021 - researchsquare.com
Background: Neuronal survival after spinal cord ischemia-reperfusion injury (SCII) is a major
factor affecting the motor function. Recently, matrix metalloproteinase-7 (MMP-7) plays an …

[PDF][PDF] КОНЦЕНТРАЦІЯ С-РЕАКТИВНОГО БІЛКА ТА ВМІСТ МОЛЕКУЛ СЕРЕДНЬОЇ МОЛЕКУЛЯРНОЇ МАСИ У ПЛАЗМІ КРОВІ ХВОРИХ НА ОСТЕОАРТРИТ …

Ю Тугаров, А Юет, Є Торгало, К Дворщенко - В І С НИ К - library.univ.kiev.ua
Метою роботи було визначити концентрацію С-реактивного білка та вміст молекул
середньої молекулярної маси у плазмі крові хворих на остеоартрит після SARS-CoV2 …

Targeting the αv Integrins in Fibroproliferative Disease

CB Nanthakumar, RJD Hatley, RJ Slack - 2020 - books.rsc.org
Fibrosis is the formation of abnormal scar tissue following repeated tissue injury, leading to
the disruption of extracellular matrix (ECM) homeostasis with loss of tissue architecture and …

[PDF][PDF] Chronic kidney disease–mechanisms of progression in companion animals

BN Lourenço - 2019 - getd.libs.uga.edu
Chronic kidney disease (CKD) affects up to 1.4% of the general canine population10 and
10% of geriatric dogs presented to referral hospitals. 9 Of these, approximately 52 to 90 …

Transcriptional trajectories of human kidney disease progression

PE Cippà, B Sun, J Liu, L Chen, M Naesens… - bioRxiv, 2018 - biorxiv.org
Our molecular understanding of clinical conditions progressing from acute organ injury to
irreversible dysfunction is limited. We used renal transplantation as a model to characterize …