Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury
J Qiang, R Yang, X Li, X Xu, M Zhou, X Ji, Y Lu… - International …, 2024 - Elsevier
Sepsis is a systemic inflammatory disease that is caused by a dysregulated host response to
infection and is a life-threatening organ dysfunction that affects many organs, which includes …
infection and is a life-threatening organ dysfunction that affects many organs, which includes …
The emerging role of mtDNA release in sepsis: Current evidence and potential therapeutic targets
Q Hong, S Zhu, Y Yu, Y Ren, L Jin… - Journal of Cellular …, 2024 - Wiley Online Library
Sepsis is a systemic inflammatory reaction caused by infection, and severe sepsis can
develop into septic shock, eventually leading to multiorgan dysfunction and even death. In …
develop into septic shock, eventually leading to multiorgan dysfunction and even death. In …
An Updated Review on Nelumbo Nucifera Gaertn: Chemical Composition, Nutritional Value and Pharmacological Activities
B Sahu, M Sahu, M Sahu, M Yadav… - Chemistry & …, 2024 - Wiley Online Library
Nelumbo nucifera Gaertn is a recognised herbal plant in ancient medical sciences. Each
portion of the plant leaf, flower, seed and rhizome is utilised for nutritional and medicinal …
portion of the plant leaf, flower, seed and rhizome is utilised for nutritional and medicinal …
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury
Q Li, L Ke, D Yu, H Xu, Z Zhang, R Yu… - Journal of Medicinal …, 2024 - ACS Publications
Mitogen-activated protein kinase-interacting protein kinases (MNKs) and phosphorylate
eukaryotic initiation factor 4E (p-eIF4E) play a critical role in regulating mRNA translation …
eukaryotic initiation factor 4E (p-eIF4E) play a critical role in regulating mRNA translation …
[HTML][HTML] Novel insights into the regulatory role of N6-methyladenosine methylation modified autophagy in sepsis
CF Bi, J Liu, XD Hu, LS Yang, JF Zhang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. It is characterized by high morbidity and mortality and one of the major …
response to infection. It is characterized by high morbidity and mortality and one of the major …
Gypenoside XLIX alleviates acute liver injury: Emphasis on NF-κB/PPAR-α/NLRP3 pathways
M Zhou, Y Cao, S Xie, Y Xiang, M Li, H Yang… - International …, 2024 - Elsevier
Liver is one of the vital organs in the human body and liver injury will have a very serious
impact on human damage. Gypenoside XLIX is a PPAR-α activator that inhibits the …
impact on human damage. Gypenoside XLIX is a PPAR-α activator that inhibits the …
Autophagy activation alleviates the LPS‐induced inflammatory response in endometrial epithelial cells in dairy cows
J Dong, B Ji, Y Jiang, K Liu, L Guo, L Cui… - American Journal of …, 2024 - Wiley Online Library
Problem Endometritis is a common disease that affects dairy cow reproduction. Autophagy
plays a vital role in cellular homeostasis and modulates inflammation by regulating …
plays a vital role in cellular homeostasis and modulates inflammation by regulating …
[HTML][HTML] Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model
Objective (s): Sepsis poses a significant threat to human life, rendering it a burdensome
medical disease. Despite significant advancements, the current state of medical science still …
medical disease. Despite significant advancements, the current state of medical science still …