The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Arthritic injuries happen frequently during a lifetime due to accidents, sports, aging,
diseases, etc. Such injuries can be cartilage/bone injuries, tendon injuries, ligament injuries …

Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The
characteristic of RA is gradual joint deterioration. Current RA treatment alleviates signs such …

Owing to the disseminating resistance among pathogenic bacteria, especially Klebsiella
pneumoniae, there is a high need for alternate compounds with antibacterial activity. Herein …

Melanoma is a highly aggressive form of skin cancer with limited therapeutic options.
Chemo-photothermal combination therapy has demonstrated potential for effectively treating …

Introduction Metformin hydrochloride (metformin HCL), a first-line drug treating diabetes type
II, was known to cause severe gastritis, so seeking a non-oral dosage form was the new …

Conventional RA treatments required prolonged therapy courses that have been
accompanied with numerous side effects impairing the patient's quality of life. Therefore …

The clinical utility of doxorubicin is compromised due to dose related toxic side effects and
limited oral bioavailability with no oral formulation being marketed. Enhancement of …

Curcumin (CU) is a natural polyphenolic phytoingredient. CU has anti-inflammatory, anti-
oxidant, and anticancer activities. The poor solubility, bioavailability, and stability of CU …

Simvastatin (SMV), a cholesterol-lowering agent, has antioxidant and anti-inflammatory
effects. Nevertheless, the oral use of SMV is linked with poor systemic bioavailability owing …