Transcript termination is essential for accurate gene expression and the removal of RNA
polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are …

Bacterial transcription termination, described mostly for Escherichia coli, occurs in three
recognized ways: intrinsic termination, an activity only of the core RNAP enzyme and …

Large genetic engineering projects require more cistrons and consequently more strong and
reliable transcriptional terminators. We have measured the strengths of a library of …

The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …

The process of transcription termination is essential to proper expression of bacterial genes
and, in many cases, to the regulation of bacterial gene expression. Two types of bacterial …

In bacteria, transcription and translation take place in the same cellular compartment.
Therefore, a messenger RNA can be translated as it is being transcribed, a process known …

RNA polymerase is a ratchet machine that oscillates between productive and backtracked
states at numerous DNA positions. Since its first description 15 years ago, backtracking—the …

The transcriptome-wide contributions of Rho-dependent and intrinsic (Rho-independent)
transcription termination mechanisms in bacteria are unclear. By sequencing released …

Efficient and accurate termination is required for gene transcription in all living organisms,.
Cellular RNA polymerases in both bacteria and eukaryotes can terminate their transcription …

Summary RNA polymerase II (RNAPII) transcription involves initiation from a promoter,
transcriptional elongation through the gene, and termination in the terminator region. In …