Neutrophils or polymorphonuclear leukocytes (PMN) are key participants in the innate
immune response for their ability to execute different effector functions. These cells express …

Inflammasome signalling is an emerging pillar of innate immunity and has a central role in
the regulation of gastrointestinal health and disease. Activation of the inflammasome …

Infection is a dynamic biological process underpinned by a complex interplay between the
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …

Neutrophils are the most prevalent immune cells in circulation, but the repertoire of
canonical inflammasomes in neutrophils and their respective involvement in neutrophil IL …

Pyroptosis is a proinflammatory mode of lytic cell death mediated by accumulation of plasma
membrane (PM) macropores composed of gasdermin‐family (GSDM) proteins. It facilitates …

The NLRP3 inflammasome is a cytosolic multimeric protein platform that leads to the
activation of the protease zymogen, caspase-1 (CASP1). Inflammasome activation mediates …

Helicobacter pylori is a spiral‐shaped gram‐negative bacterium. Its infection is mainly
transmitted via oral‐oral and fecal‐oral routes usually during early childhood. It can achieve …

Background Recently, many studies have reported that some botanicals and natural
products were able to regulate NOD-like receptor signaling. NOD-like receptors (NLRs) …

Simple Summary NLRP3 inflammasome is a cytoplasmic multiprotein complex that
assembles in response to cellular distress and promotes maturation and release of the …

In this paper, we present a literature review of the role of CXC motif chemokine ligand 1
(CXCL1) in physiology, and in selected major non-cancer diseases of the cardiovascular …