[HTML][HTML] Superantigen recognition and interactions: functions, mechanisms and applications
AM Deacy, SKE Gan, JP Derrick - Frontiers in Immunology, 2021 - frontiersin.org
Superantigens are unconventional antigens which recognise immune receptors outside
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …
[HTML][HTML] Update on targeted cancer therapies, single or in combination, and their fine tuning for precision medicine
SS Bashraheel, A Domling, SK Goda - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Background Until recently, patients who have the same type and stage of cancer all receive
the same treatment. It has been established, however, that individuals with the same …
the same treatment. It has been established, however, that individuals with the same …
[HTML][HTML] Identification of a novel fully human anti-toxic shock syndrome toxin (TSST)-1 single-chain variable fragment antibody averting TSST-1-induced mitogenesis …
Background Staphylococcal superantigens are virulence factors that help the pathogen
escape the immune system and develop an infection. Toxic shock syndrome toxin (TSST)-1 …
escape the immune system and develop an infection. Toxic shock syndrome toxin (TSST)-1 …
[HTML][HTML] Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate. In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer …
SS Bashraheel, SK Goda - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial superantigens (SAgs) are effective T-cell stimulatory molecules that lead to
massive cytokine production. Superantigens crosslink between MHC class II molecules on …
massive cytokine production. Superantigens crosslink between MHC class II molecules on …
[PDF][PDF] Superantigens, superantigen-like proteins and superantigen derivatives for cancer treatment.
JY Chen - European Review for Medical & Pharmacological …, 2021 - europeanreview.org
OBJECTIVE: Bacterial superantigens (SAgs) are proteins produced by few types of bacteria
that have been linked to several human diseases. Due to their potent in vitro and in vivo …
that have been linked to several human diseases. Due to their potent in vitro and in vivo …
Downregulation of CYP17A1 by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties
MY Aljaber, NN Orie, A Raees, S Kraiem… - Future Science …, 2022 - Future Science
Aim: To investigate the effect of 20-hydroxyecdysone on steroidogenic pathway genes and
plasma progesterone, and its potential impact on vascular functions. Methods: Chimeric …
plasma progesterone, and its potential impact on vascular functions. Methods: Chimeric …
[HTML][HTML] 20-Hydroxyecdysone dilates muscle arterioles in a nitric oxide-dependent, estrogen ER-β receptor-independent manner
NN Orie, A Raees, MY Aljaber, N Mohamed-Ali… - Phytomedicine Plus, 2021 - Elsevier
Background 20-hydroxyecdysone is an ecdysteroid which is abundant in plants and insects
and has anabolic potentials in mammals. It was recently shown to have affinity for estrogen …
and has anabolic potentials in mammals. It was recently shown to have affinity for estrogen …
Studies on Superantigens and Antibody Directed Enzyme Prodrug Therapy for Tolerable Targeted Cancer Treatment
S Bashraheel - 2019 - research.rug.nl
Conventional cancer therapies such as Radiotherapy, chemotherapy and surgery are often
associated with severe side effects due to the lack of specificity to tumor cells. Targeted …
associated with severe side effects due to the lack of specificity to tumor cells. Targeted …