Background Abnormal expression of CEACAM6 observed on the ileal epithelium in Crohn's
disease (CD) patients allows adherent-invasive Escherichia coli (AIEC) to colonize gut …

The hypothesis postulating that Mycobacterium avium paratuberculosis (MAP) is the cause
of Crohn's disease (CD) has been circulating for many years. Advances in molecular …

Background Although bacteria are implicated in the pathogenesis of chronic inflammatory
bowel diseases (IBD), mechanisms of intestinal injury and immune activation remain …

Background Although colonoscopy is useful for differentiating between Crohn's disease
(CD) and intestinal tuberculosis (ITB), the technique has limitations. We developed a …

Several lines of evidence suggest that adherent‐invasive Escherichia coli (AIEC) strains
play an important role in Crohn's disease (CD). The objective of this study was to investigate …

Inflammatory bowel disease (IBD) is characterized by activation of both the innate and
adaptive immune system in genetically susceptible individuals, resulting in chronic intestinal …

The majority of patients with Crohn's disease (CD) require surgery during the course of their
disease, but such surgery is typically not curative. Although some studies suggest that the …

Background Crohn's disease is a multifactorial disease in which an aberrant immune
response to commensal intestinal microbiota leads to chronic inflammation. The small …

Inflammation is important for antimicrobial defense and for tissue repair after trauma. The
inflammatory response and its resolution are both active processes that must be tightly …

The possibility of an infectious origin in inflammatory bowel disease (IBD) has been
postulated since the first description of Crohn's disease (CD). Many observations implicate …