Background: Evidence supports the role of adherent invasive Escherichia coli (AIEC) in the
pathogenesis of inflammatory bowel disease (IBD). However, little is known about the …

We previously demonstrated that Vibrio cholerae is able to colonize the intestine of the fly to
produce a lethal infection. Here we present the results of a genetic screen undertaken to …

The etiology of Crohn's disease (CD) is complex and involves both host susceptibility factors
(ie, the presence of particular genetic alleles) and environmental factors, including bacteria …

Many data coming from animal models and clinical observations support an involvement of
intestinal microbiota in the pathogenesis of Crohn's disease (CD). It is hypothesized in fact …

Adherent-invasive Escherichia coli (AIEC) strain LF82, isolated from patients with Crohn's
disease, invades gut epithelial cells, and replicates in macrophages contributing to chronic …

Introduction/background Inflammatory bowel disease (IBD) results from complex interactions
between: host genome, immune system, mucosa, bacteria, and environment. Sources of …

Mice of the C57BL/6 strain develop acute ileal inflammation after infection with the
protozoan parasite Toxoplasma gondii. This pathology resembles many key features of …

The etiopathogenesis of Crohn's disease (CD) is still controversial: several genetic,
immunologic, and environmental factors, including some bacteria, have been implicated …

Involvement of intestinal microbes in the pathogenesis of chronic inflammatory bowel
diseases (IBD, including Crohn disease and ulcerative colitis) is well established. However …

We have demonstrated that SlyA activates fimB expression and hence type 1 fimbriation, a
virulence factor in Escherichia coli. SlyA is shown to bind to two operator sites (O SA1 and O …