Horizons in the evolution of aging
T Flatt, L Partridge - BMC biology, 2018 - Springer
Between the 1930s and 50s, evolutionary biologists developed a successful theory of why
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
Evolution of ageing as a tangle of trade-offs: energy versus function
AA Maklakov, T Chapman - Proceedings of the Royal …, 2019 - royalsocietypublishing.org
Despite tremendous progress in recent years, our understanding of the evolution of ageing
is still incomplete. A dominant paradigm maintains that ageing evolves due to the competing …
is still incomplete. A dominant paradigm maintains that ageing evolves due to the competing …
Reproductive senescence: new perspectives in the wild
JF Lemaître, JM Gaillard - Biological Reviews, 2017 - Wiley Online Library
According to recent empirical studies, reproductive senescence, the decline in reproductive
success with increasing age, seems to be nearly ubiquitous in the wild. However, a clear …
success with increasing age, seems to be nearly ubiquitous in the wild. However, a clear …
Is antagonistic pleiotropy ubiquitous in aging biology?
SN Austad, JM Hoffman - Evolution, medicine, and public health, 2018 - academic.oup.com
Abstract Lay Summary: An evolutionary mechanism of aging was hypothesized 60 years
ago to be the genetic trade-off between early life fitness and late life mortality. Genetic …
ago to be the genetic trade-off between early life fitness and late life mortality. Genetic …
The role of telomeres in the mechanisms and evolution of life-history trade-offs and ageing
AJ Young - … Transactions of the Royal Society B …, 2018 - royalsocietypublishing.org
Evolutionary biology and biomedicine have seen a surge of recent interest in the possibility
that telomeres play a role in life-history trade-offs and ageing. Here, I evaluate alternative …
that telomeres play a role in life-history trade-offs and ageing. Here, I evaluate alternative …
Sex gap in aging and longevity: can sex chromosomes play a role?
It is well known that women live longer than men. This gap is observed in most human
populations and can even reach 10–15 years. In addition, most of the known super …
populations and can even reach 10–15 years. In addition, most of the known super …
The naked mole-rat as a model for healthy aging
Naked mole-rats (NMRs, Heterocephalus glaber) are the longest-lived rodents with a
maximum life span exceeding 37 years. They exhibit a delayed aging phenotype and …
maximum life span exceeding 37 years. They exhibit a delayed aging phenotype and …
[HTML][HTML] Motivational shifts in aging monkeys and the origins of social selectivity
L Almeling, K Hammerschmidt, H Sennhenn-Reulen… - Current Biology, 2016 - cell.com
As humans age, they become more selective regarding their personal goals [1] and social
partners [2]. Whereas the selectivity in goals has been attributed to losses in resources (eg …
partners [2]. Whereas the selectivity in goals has been attributed to losses in resources (eg …
The expensive germline and the evolution of ageing
AA Maklakov, S Immler - Current Biology, 2016 - cell.com
The trade-off between survival and reproduction is the bedrock of the evolutionary theory of
ageing. The reproductive system regulates ageing of the soma, and removal of germ cells …
ageing. The reproductive system regulates ageing of the soma, and removal of germ cells …
An evolutionary perspective on why food overconsumption impairs cognition
MP Mattson - Trends in cognitive sciences, 2019 - cell.com
Brain structures and neuronal networks that mediate spatial navigation, decision-making,
sociality, and creativity evolved, in part, to enable success in food acquisition. Here, I discuss …
sociality, and creativity evolved, in part, to enable success in food acquisition. Here, I discuss …