An overview of apoptosis assays detecting DNA fragmentation

P Majtnerová, T Roušar - Molecular biology reports, 2018 - Springer
Apoptosis has been recognized as a type of programmed cell death connected with
characteristic morphological and biochemical changes in cells. This programmed cell death …

Classification, functions, and clinical relevance of extracellular vesicles

E Van der Pol, AN Böing, P Harrison, A Sturk… - Pharmacological …, 2012 - ASPET
Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …

Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy

K Hu, L Xie, Y Zhang, M Hanyu, Z Yang… - Nature …, 2020 - nature.com
The use of photothermal agents (PTAs) in cancer photothermal therapy (PTT) has shown
promising results in clinical studies. The rapid degradation of PTAs may address safety …

A metal‐organic framework (MOF) Fenton nanoagent‐enabled nanocatalytic cancer therapy in synergy with autophagy inhibition

B Yang, L Ding, H Yao, Y Chen, J Shi - Advanced materials, 2020 - Wiley Online Library
Nanocatalytic medicine has been developed recently to trigger intratumoral generation of
highly toxic reactive oxygen species (ROS) for cancer therapy, which, unfortunately, suffers …

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

C Rogers, T Fernandes-Alnemri, L Mayes… - Nature …, 2017 - nature.com
Apoptosis is a genetically regulated cell suicide programme mediated by activation of the
effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and …

Comparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast …

S Gurunathan, JH Park, JW Han… - International journal of …, 2015 - Taylor & Francis
Background Recently, the use of nanotechnology has been expanding very rapidly in
diverse areas of research, such as consumer products, energy, materials, and medicine …

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

L Galluzzi, BS Pedro, I Vitale, SA Aaronson… - Cell Death & …, 2015 - nature.com
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable
manner, as a result of their immediate structural breakdown. Such an unavoidable variant of …

[HTML][HTML] Acalypha indica Linn: biogenic synthesis of silver and gold nanoparticles and their cytotoxic effects against MDA-MB-231, human breast cancer cells

C Krishnaraj, P Muthukumaran, R Ramachandran… - Biotechnology …, 2014 - Elsevier
This study reports the in vitro cytotoxic effect of biologically synthesized silver and gold
nanoparticles against MDA-MB-231, human breast cancer cells. Formation of silver and gold …

Morphologic and biochemical hallmarks of apoptosis

A Saraste, K Pulkki - Cardiovascular research, 2000 - academic.oup.com
Apoptosis is characterised by a series of typical morphological features, such as shrinkage
of the cell, fragmentation into membrane-bound apoptotic bodies and rapid phagocytosis by …

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

WC Earnshaw, LM Martins… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Apoptosis is a genetically programmed, morphologically distinct form of cell death
that can be triggered by a variety of physiological and pathological stimuli. Studies …