Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases

H Zalpoor, M Nabi-Afjadi, R Forghaniesfidvajani… - Cellular & molecular …, 2022 - Springer
The Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is
involved in many immunological processes, including cell growth, proliferation …

Epigenetic modifications in gastric cancer: Focus on DNA methylation

V Ebrahimi, A Soleimanian, T Ebrahimi, R Azargun… - Gene, 2020 - Elsevier
Gastric cancer is a complex heterogeneous disease which is the fourth prevalent
malignancy worldwide. Although, several diagnosis and treatment are available for the …

Curcumin-loaded mesenchymal stem cell–derived exosomes efficiently attenuate proliferation and inflammatory response in rheumatoid arthritis fibroblast-like …

X He, C Zhang, S Amirsaadat, AT Jalil… - Applied Biochemistry …, 2023 - Springer
This study aimed to evaluate the potential of mesenchymal stem cell–derived exosomes
loaded with curcumin (Curc-Exos) as an effective therapeutic strategy for rheumatoid arthritis …

Autophagy induced by Helicobacter Pylori infection can lead to gastric cancer dormancy, metastasis, and recurrence: new insights

A Akbari, SM Noorbakhsh Varnosfaderani, MS Haeri… - Human Cell, 2024 - Springer
According to the findings of recent research, Helicobacter Pylori (H. pylori) infection is not
only the primary cause of gastric cancer (GC), but it is also linked to the spread and invasion …

[HTML][HTML] Research progress in the role and mechanism of Cadherin-11 in different diseases

X Chen, H Xiang, S Yu, Y Lu, T Wu - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Cadherin is an important cell-cell adhesion molecule, which mediates intercellular adhesion
through calcium dependent affinity interaction. Cadherin-11 (CDH11, OB-cadherin) is a …

Cell‑free DNA as a liquid biopsy for early detection of gastric cancer

ZB Huang, HT Zhang, B Yu, DH Yu - Oncology Letters, 2021 - spandidos-publications.com
Gastric cancer (GC) is one of the most common malignant tumors with poor prognosis
worldwide, mainly due to the lack of suitable modalities for population‑based screening and …

DNA methylation: an important biomarker and therapeutic target for gastric cancer

Y Zeng, H Rong, J Xu, R Cao, S Li, Y Gao… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence
and development are closely related to epigenetic modifications. Methylation of DNA before …

Identification of the subtypes of gastric cancer based on DNA methylation and the prediction of prognosis

T Li, X Chen, M Gu, A Deng, C Qian - Clinical epigenetics, 2020 - Springer
Background Gastric cancer (GC) is a digestive system cancer with a high mortality rate
globally. Previous experiences and studies have provided clinicians with ample evidence to …

Identification of the miRNA signature and key genes in colorectal cancer lymph node metastasis

X Wang, G Gao, Z Chen, Z Chen, M Han, X Xie… - Cancer Cell …, 2021 - Springer
Background Because its metastasis to the lymph nodes are closely related to poor
prognosis, miRNAs and mRNAs can serve as biomarkers for the diagnosis, prognosis, and …

Immunological significance of prognostic DNA methylation sites in hepatocellular carcinoma

Q Xu, Y Hu, S Chen, Y Zhu, S Li, F Shen… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) is a tumor with high morbidity and high
mortality worldwide. DNA methylation, one of the most common epigenetic changes, might …