The human microbiome: at the interface of health and disease

I Cho, MJ Blaser - Nature Reviews Genetics, 2012 - nature.com
Interest in the role of the microbiome in human health has burgeoned over the past decade
with the advent of new technologies for interrogating complex microbial communities. The …

Intestinal mucosal barrier function in health and disease

JR Turner - Nature reviews immunology, 2009 - nature.com
Mucosal surfaces are lined by epithelial cells. These cells establish a barrier between
sometimes hostile external environments and the internal milieu. However, mucosae are …

[HTML][HTML] Gut bacteria in health and disease

EMM Quigley - Gastroenterology & hepatology, 2013 - ncbi.nlm.nih.gov
A new era in medical science has dawned with the realization of the critical role of the
“forgotten organ,” the gut micro-biota, in health and disease. Central to this beneficial …

[HTML][HTML] Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?

GL Hold, M Smith, C Grange, ER Watt… - World journal of …, 2014 - ncbi.nlm.nih.gov
Our understanding of the microbial involvement in inflammatory bowel disease (IBD)
pathogenesis has increased exponentially over the past decade. The development of newer …

Probiotics, prebiotics, and synbiotics

M De Vrese, J Schrezenmeir - Food biotechnology, 2008 - Springer
According to the German definition, probiotics are defined viable microorganisms, sufficient
amounts of which reach the intestine in an active state and thus exert positive health effects …

Skin microbiota: a source of disease or defence?

AL Cogen, V Nizet, RL Gallo - British journal of dermatology, 2008 - academic.oup.com
Microbes found on the skin are usually regarded as pathogens, potential pathogens or
innocuous symbiotic organisms. Advances in microbiology and immunology are revising our …

Prebiotics and probiotics; modifying and mining the microbiota

EMM Quigley - Pharmacological research, 2010 - Elsevier
A new era in medical science has dawned with the realization of the critical role of the
“forgotten organ”, the enteric microbiota, in generating a variety of functions which sustain …

Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APC Min/+ mice

Y Li, P Kundu, SW Seow, CT de Matos… - …, 2012 - academic.oup.com
Chronic inflammation is increasingly recognized as a major contributor of human colorectal
cancer (CRC). While gut microbiota can trigger inflammation in the intestinal tract, the …

Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in vitro approach using a continuous culture colonic model system

S Maccaferri, B Vitali, A Klinder, S Kolida… - Journal of …, 2010 - academic.oup.com
Objectives Rifaximin, a rifamycin derivative, has been reported to induce clinical remission
of active Crohn's disease (CD), a chronic inflammatory bowel disorder. In order to …

Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases

L Gentschew, LR Ferguson - Molecular nutrition & food …, 2012 - Wiley Online Library
Inflammatory bowel diseases (IBD s), C rohn's disease (CD), and ulcerative colitis (UC) are
chronic inflammatory conditions, which are increasing in incidence, prevalence, and …