[HTML][HTML] Pediatric acute lymphoblastic leukemia

H Inaba, CG Mullighan - Haematologica, 2020 - ncbi.nlm.nih.gov
The last decade has witnessed great advances in our understanding of the genetic and
biological basis of childhood acute lymphoblastic leukemia (ALL), the development of …

[HTML][HTML] Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data

L Lenk, A Alsadeq, DM Schewe - Cancer and Metastasis Reviews, 2020 - Springer
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. One of the major
clinical challenges is adequate diagnosis and treatment of central nervous system (CNS) …

Prognostic factors for CNS control in children with acute lymphoblastic leukemia treated without cranial irradiation

J Tang, J Yu, J Cai, L Zhang, S Hu… - Blood, The Journal …, 2021 - ashpublications.org
To identify the prognostic factors that are useful to improve central nervous system (CNS)
control in children with acute lymphoblastic leukemia (ALL), we analyzed the outcome of …

[HTML][HTML] A narrative review of central nervous system involvement in acute leukemias

D Deak, N Gorcea-Andronic, V Sas… - Annals of …, 2021 - ncbi.nlm.nih.gov
Acute leukemias (both myeloid and lymphoblastic) are a group of diseases for which each
year more successful therapies are implemented. However, in a subset of cases the overall …

Remission, treatment failure, and relapse in pediatric ALL: an international consensus of the Ponte-di-Legno Consortium

S Buchmann, M Schrappe, A Baruchel… - Blood, The Journal …, 2022 - ashpublications.org
Abstract Comparison of treatment strategies in de novo pediatric acute lymphoblastic
leukemia (ALL) requires standardized measures of efficacy. Key parameters that define …

Central nervous system status is prognostic in T-cell acute lymphoblastic leukemia: a Children's Oncology Group report

NP Gossai, M Devidas, Z Chen, BL Wood… - Blood, 2023 - ashpublications.org
To determine the prognostic significance of central nervous system (CNS) leukemic
involvement in newly diagnosed T-cell acute lymphoblastic leukemia (T-ALL), outcomes on …

Sex‐based disparities in outcome in pediatric acute lymphoblastic leukemia: a Children's Oncology Group report

S Gupta, DT Teachey, Z Chen, KR Rabin… - Cancer, 2022 - Wiley Online Library
Background Boys with acute lymphoblastic leukemia (ALL) have historically experienced
inferior survival compared to girls. This study determined whether sex‐based disparities …

How I prevent and treat central nervous system disease in adults with acute lymphoblastic leukemia

NE Kopmar, RD Cassaday - Blood, 2023 - ashpublications.org
The central nervous system (CNS) is the most important site of extramedullary disease in
adults with acute lymphoblastic leukemia (ALL). Although CNS disease is identified only in a …

[HTML][HTML] Integrin-mediated adhesion and chemoresistance of acute lymphoblastic leukemia cells residing in the bone marrow or the central nervous system

BFSS Scharff, S Modvig, HV Marquart… - Frontiers in …, 2020 - frontiersin.org
Acute Lymphoblastic Leukemia (ALL) is the most common cancer in childhood. Despite a
significantly improved prognosis over the last decade with a 5-years survival rate of~ 90 …

[HTML][HTML] Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of …

C Mirian, M Thastrup, R Mathiasen… - Fluids and Barriers of …, 2024 - Springer
Background The cerebrospinal fluid (CSF) proteome could offer important insights into
central nervous system (CNS) malignancies. To advance proteomic research in pediatric …